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Anti-CASP3 PHOSPHO Antibody


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SKU Description Amount Price Availability*  
TA325294 Rabbit Polyclonal Caspase 3 (Ser150) Antibody (Phospho-specific) 100ul 325
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Also for CASP3 (NM_004346)
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OriGene Data

ImmunogenThe antiserum was produced against A synthesized peptide derived from human Caspase 3 around the phosphorylation site of Serine 150
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1 mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 1:500-1:2000; IHC: 1:50-1:200
Predicted MW Explanation 34kDa
BufferRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide.

Reference Data

Target NameHomo sapiens caspase 3, apoptosis-related cysteine peptidase (CASP3), transcript variant alpha
Alternative NameCPP32; CPP32B; SCA-1
Database LinkNP_004337
Entrez Gene 836 Human
Entrez Gene 12367 Mouse
Entrez Gene 25402 Rat
FunctionThis gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme.
Related PathwayES Cell Differentiation/IPSProteaseDruggable Genome MAPK signaling pathwayp53 signaling pathwayApoptosisNatural killer cell mediated cytotoxicityAlzheimer's diseaseParkinson's diseaseMore Pathways >>

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* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of Caspase 3 phosphorylation expression in Etoposide treated Jurkat whole cell lysates,The lane on the left is treated with the antigen-specific peptide.


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