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Home Antibody All anti-CARD11 antibodies

Anti-CARD11 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA302440
  • Goat Polyclonal Antibody against CARD11
  • FREE positive control: HEK293T cell transient overexpression lysate (LC403162) , 20ug
100ug $325 3-7 Days
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WB(2)
IHC(1)
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Also for CARD11 (NM_032415)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenPeptide with sequence C-QRKTIWVDEDQL, from the C Terminus of the protein sequence according to NP_115791.2.
Clone Name IsotypeGoat IgG
Species ReactivityHuman, Mouse Concentration0.5 mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsELISA: 1:32,000. WB: 1-3µg/ml.
BufferSupplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Reference Data

Target NameHomo sapiens caspase recruitment domain family, member 11 (CARD11)
Alternative NameBENTA; BIMP3; CARMA1; IMD11; PPBL
Database LinkNP_115791
FunctionThe protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10. [provided by RefSeq].
Related Pathway

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WB Image
TA302440 staining (1µg/ml) of human Jurkat cells (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.
WB Image
HEK293 overexpressing CARD11 (RC222740) and probed with TA302440 (mock transfection in first lane)
IHC Image
TA302440 (2µg/ml) staining of paraffin embedded Human Spleen. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

 

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