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Home Antibody All anti-CAMLG antibodies

Anti-CAMLG TRUEMAB Antibody Clone OTI2H3

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA504363 CAMLG mouse monoclonal antibody, clone OTI2H3 (formerly 2H3) 100ul $325 In Stock
LC419768 CAMLG HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF504363 Carrier-free (BSA/glycerol-free) CAMLG mouse monoclonal antibody, clone OTI2H3 (formerly 2H3) 100ug $450 3-4 weeks
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WB(1)
IF(1)
FC(2)
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Also for CAMLG (NM_001745)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human CAMLG(NP_001736) produced in HEK293T cell.
Clone NameClone OTI2H3 IsotypeIgG1
Species ReactivityHuman Concentration0.63 mg/ml
Guaranteed Application *WB, IF, FC Suggested Dilutions WB 1:2000, IF 1:100, FLOW 1:100,
Predicted MW Explanation 32.8 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens calcium modulating ligand (CAMLG)
Alternative NameCAML
Database LinkNP_001736
Entrez Gene 819 Human
FunctionThe immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin. [provided by RefSeq, Jul 2008].
Related PathwayDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CAMLG (RC218292, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CAMLG.
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Anti-CAMLG mouse monoclonal antibody (TA504363) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY CAMLG(RC218292).
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HEK293T cells transfected with either RC218292 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-CAMLG antibody(TA504363), and then analyzed by flow cytometry.
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Flow cytometric Analysis of Jurkat cells, using anti-CAMLG antibody(TA504363),(Red), compared to a nonspecific negative control antibody,(Blue).
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