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Home Antibody All anti-BTK antibodies

Anti-BTK TRUEMAB Antibody Clone OTI3D11

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA501092 anti-BTK mouse monoclonal antibody, clone OTI3D11 (formerly 3D11) 100ul $325 In Stock
LC424947 BTK HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF501092 Carrier-free (BSA/glycerol-free) BTK mouse monoclonal antibody, clone OTI3D11 (formerly 3D11) 100ug $450 3-4 weeks
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WB(1)
IHC(3)
IF(1)
FC(1)

OriGene Data

ImmunogenFull length human recombinant protein of human BTK (NP_000052) produced in HEK293T cell.
Clone NameClone OTI3D11 IsotypeIgG3
Species ReactivityHuman Concentration0.5 mg/ml
Guaranteed Application *WB, IHC, IF, FC Suggested DilutionsWB 1:2000, IHC 1:50, IF 1:100, Flow 1:100
Predicted MW Explanation 76.3kDa
BufferPBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens Bruton agammaglobulinemia tyrosine kinase (BTK), transcript variant 1
Alternative NameAGMX1; AT; ATK; BPK; IMD1; PSCTK1; XLA
Database LinkNP_000052
Entrez Gene 695 Human
FunctionThe protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement.
Related PathwayProtein KinaseDruggable Genome B cell receptor signaling pathwayFc epsilon RI signaling pathwayPrimary immunodeficiency

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY BTK (RC211582, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-BTK.
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Immunohistochemical staining of paraffin-embedded Kidney tissue within the normal limits using anti-BTK mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA501092, Dilution 1:50)
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Immunohistochemical staining of paraffin-embedded liver tissue within the normal limits using anti-BTK mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA501092, Dilution 1:50)
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Immunohistochemical staining of paraffin-embedded Carcinoma of liver tissue using anti-BTK mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA501092, Dilution 1:50)
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Anti-BTK mouse monoclonal antibody (TA501092) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY BTK(RC211582).
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HEK293T cells transfected with either pCMV6-ENTRY BTK(RC211582)(Red) or empty vector control plasmid(Blue) were immunostained with anti-BTK mouse monoclonal(TA501092), and then analyzed by flow cytometry.
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