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Anti-BSG Antibody EPR4053
|A synthetic peptide corresponding to residues on the C-terminus in human CD147 was used as an immunogen.|
||Tissue culture supernatant
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:1000 - 1:10000; IHC-P: 1:250 - 1:500; ICC: 1:100 - 1:250
|Does not react with Mouse, Rat. Is unsuitable for Flow Cyt or IP.|
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
|Is unsuitable for Flow Cyt or IP.
|Homo sapiens basigin (Ok blood group) (BSG), transcript variant 4|
|5F7; CD147; EMMPRIN; M6; OK; TCSF|
|CD147 is a plasma membrane protein that is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. It is also a member of the immunoglobulin superfamily (1). CD147 stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS). It may target monocarboxylate transporters SLC16A1, SLC16A3 and SLC16A8 to plasma membranes of retinal pigment epithelium and neural retina. CD147 is present only in vascular endothelium in non-neoplastic regions of the brain, whereas it is present in tumor cells but not in proliferating blood vessels in malignant gliomas (2).|
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Western blot - CD147 antibody [EPR4053]; All lanes : Anti-CD147 antibody [EPR4053] at 1/1000 dilution.Lane 1 : Jurkat cell lysate.Lane 2 : HuT-78 cell lysate.Lane 3 : A431 cell lysate.Lysates/proteins at 10 µg per lane.Performed under reducing conditions.Predicted band size : 42 kDa.
Western blot - CD147 antibody [EPR4053]; Anti-CD147 antibody [EPR4053] at 1/1000 dilution + HeLa cell lysate at 10 µg.Performed under reducing conditions.Predicted band size : 42 kDa.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - CD147 antibody [EPR4053]; TA306979, at 1/250, staining CD147 in human glioma tissue by immunohistochemistry.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - CD147 antibody [EPR4053]; TA306979, at 1/250, staining human brain tissue by immunohistochemistry.