OriGene Technologies, Inc.
Search:    
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
 
Home Antibody All anti-BSG antibodies

Anti-BSG Antibody EPR4053

div

Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306979
  • Rabbit monoclonal antibody against CD147(clone EPR4053)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC403688) , 20ug Explanation
100ul 325 In Stock
Add to Shopping Cart
WB(2)
IHC(2)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues on the C-terminus in human CD147 was used as an immunogen.
Clone NameEPR4053 IsotypeTissue culture supernatant
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:10000; IHC-P: 1:250 - 1:500; ICC: 1:100 - 1:250
BufferDoes not react with Mouse, Rat. Is unsuitable for Flow Cyt or IP.
Purification PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt or IP.

Reference Data

Target NameHomo sapiens basigin (Ok blood group) (BSG), transcript variant 4
Alternative Name5F7; CD147; EMMPRIN; M6; OK; TCSF
Database LinkNP_940993
Entrez Gene 682 Human
FunctionCD147 is a plasma membrane protein that is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. It is also a member of the immunoglobulin superfamily (1). CD147 stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS). It may target monocarboxylate transporters SLC16A1, SLC16A3 and SLC16A8 to plasma membranes of retinal pigment epithelium and neural retina. CD147 is present only in vascular endothelium in non-neoplastic regions of the brain, whereas it is present in tumor cells but not in proliferating blood vessels in malignant gliomas (2).
Related PathwayES Cell Differentiation/IPSTransmembraneDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - CD147 antibody [EPR4053]; All lanes : Anti-CD147 antibody [EPR4053] at 1/1000 dilution.Lane 1 : Jurkat cell lysate.Lane 2 : HuT-78 cell lysate.Lane 3 : A431 cell lysate.Lysates/proteins at 10 ug per lane.Performed under reducing conditions.Predicted band size : 42 kDa.
WB Image
Western blot - CD147 antibody [EPR4053]; Anti-CD147 antibody [EPR4053] at 1/1000 dilution + HeLa cell lysate at 10 ug.Performed under reducing conditions.Predicted band size : 42 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - CD147 antibody [EPR4053]; TA306979, at 1/250, staining CD147 in human glioma tissue by immunohistochemistry.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - CD147 antibody [EPR4053]; TA306979, at 1/250, staining human brain tissue by immunohistochemistry.

 

spacer
Inc 5000 Healthcare Company Copyright © 2014 OriGene Technologies, Inc. All Rights Reserved. Legal Notices.
9620 Medical Center Dr., Suite 200, Rockville, MD 20850 • 1.888.267.4436

Reproduction of any materials from this website is strictly forbidden without permission.

All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title