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Anti-BSG Antibody EPR4052
|A synthetic peptide corresponding to residues in human CD147 was used as an immunogen.|
|Human, Mouse, Rat
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:1000 - 1:10000; IHC-P: 1:250 - 1:500; ICC: 1:50 - 1:100
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Tissue culture supernatant (Protein A or G Sepharose)
|Is unsuitable for Flow Cyt or IP.
|Homo sapiens basigin (BSG), transcript variant 4|
|5F7; CD147; EMMPRIN; M6; OK; TCSF|
|CD147 is a plasma membrane protein that is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. It is also a member of the immunoglobulin superfamily (1). CD147 stimulates adjacent fibroblasts to produce matrix metalloproteinases. It may target monocarboxylate transporters SLC16A1, SLC16A3 and SLC16A8 to plasma membranes of retinal pigment epithelium and neural retina. CD147 is present only in vascular endothelium in non-neoplastic regions of the brain, whereas it is present in tumor cells but not in proliferating blood vessels in malignant gliomas (2).|
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Western blot - CD147 antibody [EPR4052]; All lanes : Anti-CD147 [EPR4052] antibody at 1/1000 dilution.Lane 1 : A431 cell lysate.Lane 2 : HeLa cell lysate.Lane 3 : Jurkat cell lysate.Lane 4 : HuT-78 cell lysate.Lysates/proteins at 10 µg per lane.Predicted band size : 42 kDa.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - CD147 antibody [EPR4052]; ab108317, at 1/250 dilution, staining CD147 in paraffin-embedded Human ovary carcinoma tissue by Immunohistochemistry.