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Home Antibody All anti-BNIP3 antibodies

Anti-BNIP3 Antibody EPR4034

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307843
  • Rabbit monoclonal antibody against NIP3 / BNIP3(clone EPR4034)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC418252) , 20ug
100ul 325 In Stock
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WB(1)
IHC(1)
IF(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human NIP3 / BNIP3 was used as an immunogen.
Clone NameEPR4034 IsotypeIgG
Species ReactivityHuman, Mouse, Rat ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1:1000 - 1:10000; IHC-P: 1:50 - 1:100; ICC/IF: 1:100 - 1:250
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt or IP.

Reference Data

Target NameHomo sapiens BCL2/adenovirus E1B 19kDa interacting protein 3 (BNIP3)
Alternative NameNIP3
Database LinkNP_004043
FunctionNIP3 / BNIP3 is a member of the BCL2/adenovirus E1B 19 kDa-interacting protein (BNIP) family. It interacts with the E1B 19 kDa protein which is responsible for the protection of virally-induced cell death, as well as E1B 19 kDa-like sequences of BCL2, also an apoptotic protector. NIP3 / BNIP3 contains a BH3 domain and a transmembrane domain, which have been associated with pro-apoptotic function. The dimeric mitochondrial protein is known to induce apoptosis, even in the presence of BCL2.
Related Pathway

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WB Image
Western blot - BNIP3 antibody [EPR4034]; All lanes : Anti-BNIP3 antibody [EPR4034] at 1/1000 dilution.Lane 1 : Jurkat cell lysate treated with etoposide.Lane 2 : Jurkat cell lysate.Lane 3 : SH-SY5Y cell lysate treated with camptothecin.Lane 4 : SH-SY5Y cell lysate.Lane 5 : MCF-7 cell lysate treated with Cocl2.Lysates/proteins at 10 µg per lane.Predicted band size : 22 kDa.Observed band size : 30 kDa .
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - BNIP3 antibody [EPR4034]; TA307843, at 1/50, staining BNIP3 in Human kidney tissue by immunohistochemistry.
IF Image
Immunocytochemistry/ Immunofluorescence - BNIP3 antibody [EPR4034]; TA307843, at 1/100, staining BNIP3 in SH-SY5Y by immunofluorescence.

 

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