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Home Antibody All anti-BIRC7 antibodies

Anti-BIRC7 TRUEMAB Antibody Clone OTI1B10

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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SKU Description Amount Price Availability*  
TA500761 anti-BIRC7 (Livin) mouse monoclonal antibody, clone OTI1B10 (formerly 1B10) 100ul $379 In Stock
LC403386 BIRC7 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF500761 Carrier-free (BSA/glycerol-free) BIRC7 mouse monoclonal antibody, clone OTI1B10 (formerly 1B10) 100ug $450 3-4 weeks
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WB(1)
IF(2)
FC(2)
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Also for BIRC7 (NM_139317)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human BIRC7 (NP_071444) produced in HEK293T cell.
Clone NameClone OTI1B10 IsotypeIgG1
Species ReactivityHuman Concentration1.1 mg/ml
Guaranteed Application *WB, IF, FC Suggested DilutionsWB 1:2000, IF 1:100, Flow 1:100
Predicted MW Explanation 32.8 kDa
BufferPBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens baculoviral IAP repeat containing 7 (BIRC7), transcript variant 1
Alternative NameKIAP; LIVIN; ML-IAP; MLIAP; RNF50
Database LinkNP_647478
Entrez Gene 79444 Human
FunctionThe protein encoded by this gene is a member of the family of inhibitor of apoptosis proteins (IAP) and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Two transcript variants encoding different isoforms have been found for this gene. The two isoforms have different antiapoptotic properties, with isoform alpha protecting cells from apoptosis induced by staurosporine and isoform b protecting cells from apoptosis induced by etoposide.
Related PathwayDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY BIRC7 (RC204906, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-BIRC7.
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Anti-BIRC7 mouse monoclonal antibody (TA500761) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY BIRC7(RC204906).
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Immunofluorescent staining of HeLa cells using anti-BIRC7 mouse monoclonal antibody (TA500761).
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Flow cytometric analysis of Hela cells, using anti-BIRC7 antibody(TA500761),(Red) compared to a nonspecific negative control antibody(TA50011)(Blue).
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Flow cytometric analysis of Jurkat cells, using anti-BIRC7 antibody(TA500761),(Red) compared to a nonspecific negative control antibody(TA50011)(Blue).
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