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Home Antibody All anti-BIRC2 antibodies

Anti-BIRC2 Antibody EPR4673

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307562
  • Rabbit monoclonal antibody against cIAP1(clone EPR4673)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400468) , 20ug Explanation
100ul 325 In Stock
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WB(1)
IHC(1)
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Also for BIRC2 (NM_001166)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human cIAP1 was used as an immunogen.
Clone NameEPR4673 IsotypeTissue culture supernatant
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:10000; IHC-P: 1:50 - 1:100; ICC: 1:50 - 1:100
BufferDoes not react with Mouse, Rat. Is unsuitable for Flow Cyt or IP.
Purification PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt or IP.

Reference Data

Target NameHomo sapiens baculoviral IAP repeat containing 2 (BIRC2), transcript variant 1
Alternative NameAPI1; c-IAP1; cIAP1; Hiap-2; HIAP2; MIHB; RNF48
Database LinkNP_001157
Entrez Gene 329 Human
FunctioncIAP1, or baculoviral IAP repeat-containing 2, is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. cIAP1 inhibits apoptosis induced by serum deprivation and menadione, a potent inducer of free radicals.
Related PathwayDruggable Genome Ubiquitin mediated proteolysisApoptosisFocal adhesionNOD-like receptor signaling pathwayPathways in cancerSmall cell lung cancerMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - cIAP1 antibody [EPR4673]; All lanes : Anti-cIAP1 antibody [EPR4673] at 1/1000 dilution.Lane 1 : Jurkat cell lysate .Lane 2 : HeLa cell lysate .Lane 3 : HT29 cell lysate.Lane 4 : HepG2 cell lysate .Lysates/proteins at 10 ug per lane.Predicted band size : 70 kDa.Observed band size : 70 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - cIAP1 antibody [EPR4673]; TA307562, at 1/50, staining cIAP1 in paraffin-embedded Human spleen tissue by Immunohistochemistry.

 

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