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Anti-BIRC2 Antibody EPR4673
Also for BIRC2 (NM_001166)
|A synthetic peptide corresponding to residues in human cIAP1 was used as an immunogen.|
||Tissue culture supernatant
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:1000 - 1:10000; IHC-P: 1:50 - 1:100; ICC: 1:50 - 1:100
|Does not react with Mouse, Rat. Is unsuitable for Flow Cyt or IP.|
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05% (Protein A or G Sepharose)
|Is unsuitable for Flow Cyt or IP.
|Homo sapiens baculoviral IAP repeat containing 2 (BIRC2), transcript variant 1|
|API1; c-IAP1; cIAP1; Hiap-2; HIAP2; MIHB; RNF48|
|cIAP1, or baculoviral IAP repeat-containing 2, is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. cIAP1 inhibits apoptosis induced by serum deprivation and menadione, a potent inducer of free radicals.|
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Western blot - cIAP1 antibody [EPR4673]; All lanes : Anti-cIAP1 antibody [EPR4673] at 1/1000 dilution.Lane 1 : Jurkat cell lysate .Lane 2 : HeLa cell lysate .Lane 3 : HT29 cell lysate.Lane 4 : HepG2 cell lysate .Lysates/proteins at 10 µg per lane.Predicted band size : 70 kDa.Observed band size : 70 kDa.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - cIAP1 antibody [EPR4673]; ab108361, at 1/50, staining cIAP1 in paraffin-embedded Human spleen tissue by Immunohistochemistry.