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Home Antibody All anti-BIRC2 antibodies

Anti-BIRC2 Antibody EPR4673

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307562
  • Rabbit monoclonal antibody against cIAP1(clone EPR4673)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400468) , 20ug
100ul 325 In Stock
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WB(1)
IHC(1)
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Also for BIRC2 (NM_001166)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human cIAP1 was used as an immunogen.
Clone NameEPR4673 IsotypeTissue culture supernatant
Species ReactivityHuman ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:10000; IHC-P: 1:50 - 1:100; ICC: 1:50 - 1:100
BufferDoes not react with Mouse, Rat. Is unsuitable for Flow Cyt or IP.
Purification PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt or IP.

Reference Data

Target NameHomo sapiens baculoviral IAP repeat containing 2 (BIRC2), transcript variant 1
Alternative NameAPI1; c-IAP1; cIAP1; Hiap-2; HIAP2; MIHB; RNF48
Database LinkNP_001157
FunctioncIAP1, or baculoviral IAP repeat-containing 2, is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. cIAP1 inhibits apoptosis induced by serum deprivation and menadione, a potent inducer of free radicals.
Related Pathway
Apoptosis
Focal Adhesion

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - cIAP1 antibody [EPR4673]; All lanes : Anti-cIAP1 antibody [EPR4673] at 1/1000 dilution.Lane 1 : Jurkat cell lysate .Lane 2 : HeLa cell lysate .Lane 3 : HT29 cell lysate.Lane 4 : HepG2 cell lysate .Lysates/proteins at 10 µg per lane.Predicted band size : 70 kDa.Observed band size : 70 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - cIAP1 antibody [EPR4673]; TA307562, at 1/50, staining cIAP1 in paraffin-embedded Human spleen tissue by Immunohistochemistry.

 

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