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Home Antibody All anti-BCL2L11 antibodies

Anti-BCL2L11 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA305980
  • Rabbit Polyclonal Bim Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC416580) , 20ug Explanation
100ug 325 3-7 Days
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WB(1)
IHC(1)
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Also for BCL2L11 (NM_006538)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenBim antibody was raised against a peptide corresponding to amino acids near the center of human Bim. The sequence is identical to that of mouse and differs from that of rat by one amino acid .
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens BCL2-like 11 (apoptosis facilitator) (BCL2L11), transcript variant 6
Alternative NameBAM; BIM; BOD
Database LinkNP_006529
Entrez Gene 10018 Human
Entrez Gene 12125 Mouse
Entrez Gene 64547 Rat
FunctionMembers in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain is a potent death domain. BH3 domain containing pro-apoptotic proteins, including Bad, Bax, Bid, Bik, and Hrk, form a growing subclass of the Bcl-2 family. A novel BH3 domain containing protein was recently identified and designated Bim or BOD in human, mouse and rat (1,2). Bim/BOD interacts with diverse members in the pro-survival Bcl-2 sub-family including Bcl-2, Bcl-xL and Bcl-w. Bim/BOD induces apoptosis. The messenger RNA of Bim is ubiquitously expressed in multiple tissues and cell lines (1,2).
Related PathwayDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of Bim in K562 (K) and A549 (A) whole cell lysates with Bim antibody at 1 ug/ml.
IHC Image
Immunohistochemistry of Bim in human skin cancer cells with Bim antibody at 20 ug/ml.

 

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