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Home Antibody All anti-BCL2L10 antibodies

Anti-BCL2L10 Antibody

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SKU Description Amount Price Availability*  
TA308442 Rabbit polyclonal antibody to Bcl-B (BCL2-like 10 (apoptosis facilitator)) 100ul $325 In Stock
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WB(1)
IHC(1)
IF(1)

OriGene Data

ImmunogenSynthetic peptide corresponding to a region within amino acids 60 and 153 of BCL2L10 (Uniprot ID#Q9HD36)
Clone Name IsotypeIgG
Species ReactivityHuman Concentration1 mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 23kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.

Reference Data

Target NameHomo sapiens BCL2-like 10 (apoptosis facilitator) (BCL2L10)
Alternative NameBCL-B; Boo; Diva
Database LinkNP_065129
Entrez Gene 10017 Human
FunctionThe protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains conserved BH4, BH1 and BH2 domains. This protein can interact with other members of BCL-2 protein family including BCL2, BCL2L1/BCL-X(L), and BAX. Overexpression of this gene has been shown to suppress cell apoptosis possibly through the prevention of cytochrome C release from the mitochondria, and thus activating caspase-3 activation. The mouse counterpart of this protein is found to interact with Apaf1 and forms a protein complex with Caspase 9, which suggests the involvement of this protein in APAF1 and CASPASE 9 related apoptotic pathway. [provided by RefSeq]
Related PathwayTransmembraneDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Sample (30 ug of whole cell lysate). A: Raji. 12% SDS PAGE. TA308442 diluted at 1:1000.
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Immunohistochemical analysis of paraffin-embedded A549 Xenograft, using BCL2L10(TA308442) antibody at 1:100 dilution.
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Immunofluorescence analysis of paraformaldehyde-fixed A431, using BCL2L10(TA308442) antibody at 1:200 dilution.
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