Home Antibody All anti-BCL2L10 antibodies
Also for BCL2L10 (NM_020396)
|Bcl-B antibody was raised against a 16 amino acid peptide from near the amino terminus of human Bcl-B.|
||ELISA, WB: 1 ug/ml, ICC: 10 ug/ml
|PBS containing 0.02% sodium azide.|
|Affinity chromatography purified via peptide column (Protein A or G Sepharose)
|Homo sapiens BCL2-like 10 (apoptosis facilitator) (BCL2L10)|
|BCL-B; Boo; Diva|
|Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-B is a recently discovered anti-apoptotic member of the Bcl-2. Unlike the mouse homolog (also known as Diva/Boo) which is predominantly expressed in ovary and testis, the human Bcl-B protein is widely expressed. Also, the human Bcl-B functions by binding to and suppressing the apoptotic activity of Bax, whereas the mouse homolog binds Bak and also interacts with the apoptosis protein Apaf-1. Despite its predicted molecular weight, Bcl-B is often at higher molecular weights, presumably due to post-translational modifications.|
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Western blot analysis of Bcl-B in Jurkat lysate with Bcl-B antibody at 1 ug/ml in the (A) absence and (B) presence of blocking peptide.
Immunocytochemistry of Bcl-B in Jurkat cells with Bcl-B antibody at 10 ug/mL.