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Home Antibody All anti-BCL2L1 antibodies

Anti-BCL2L1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308852
  • Rabbit Polyclonal antibody to BCL-x (BCL2-like 1)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC420078) , 20ug
100ul $325 3-7 Days
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WB(1)
IHC(1)
IF(1)
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Also for BCL2L1 (NM_001191)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenRecombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 178 of BCL2L1
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse Concentration0.95mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB:1:500-1:3000; IHC:1:500; IF:1:100-1:500;
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.

Reference Data

Target NameHomo sapiens BCL2-like 1 (BCL2L1), transcript variant 2
Alternative NameBcl-X; bcl-xL; BCL-XL/S; bcl-xS; BCL2L; BCLX; BCLXL; BCLXS; PPP1R52
Database LinkNP_001182
FunctionThe protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported. The longer isoform acts as an apoptotic inhibitor and the shorter form acts as an apoptotic activator. [provided by RefSeq]
Related Pathway
Apoptosis
Jak-STAT signaling pathway

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WB Image
Sample (30 ug of whole cell lysate) A:NIH-3T3 ( anti-BCL2L1 antibody diluted at 1:1000)
IHC Image
Immunohistochemical analysis of paraffin-embedded SW480 xenograft, using BCL2L1(anti-BCL2L1 antibody) antibody at 1:500 dilution.
IF Image
Immunofluorescence analysis of methanol-fixed A549, using BCL-x(anti-BCL2L1 antibody) antibody at 1:500 dilution.

 

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