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Home Antibody All anti-BCAR3 antibodies

Anti-BCAR3 Antibody Polyclonal

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA319747
  • Rabbit Polyclonal BCAR3 Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401187) , 20ug Explanation
100ug 325 3-7 Days
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WB(1)
IF(1)

OriGene Data

ImmunogenBCAR3 antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human BCAR3.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IF Suggested DilutionsWB: 1 - 2 ug/ml, IF: 20 ug/ml
Predicted MW Explanation 91 kDa
BufferBCAR3 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification BCAR3 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens breast cancer anti-estrogen resistance 3 (BCAR3), transcript variant 1
Alternative NameNSP2; SH2D3B
Database LinkNP_001248337
Entrez Gene 8412 Human
Entrez Gene 29815 Mouse
Entrez Gene 310838 Rat
FunctionBCAR3 Antibody: Breast cancer anti-estrogen resistance 3 (BCAR3) was identified in the search for genes involved in the development of estrogen resistance. It contains a putative src homology 2 (SH2) domain and is partly homologous to the cell division cycle protein CDC48. BCAR3 is a binding partner with Cas, an adapter molecule that plays a role in cell proliferation, survival, cell adhesion, and mobility. BCAR3 functions synergistically with Cas to enhance Src activation and promote cell migration, and has been suggested to regulate Cas/Src association, Src kinase activity, and breast cancer adhesion signaling.
Related PathwayDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of BCAR3 in mouse kidney tissue lysate with BCAR3 antibody at A) 1 and (B) 2 ug/mL.
IF Image
Immunofluorescence of BCAR3 in human kidney tissue with BCAR3 antibody at 20 ug/mL.

 

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