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Anti-BCAR3 Antibody Polyclonal
Also for BCAR3 (NM_001261408)
|BCAR3 antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human BCAR3.|
|Human, Mouse, Rat
||ELISA, WB: 1 - 2 ug/ml, IF: 20 ug/ml
|BCAR3 Antibody is supplied in PBS containing 0.02% sodium azide.|
|BCAR3 Antibody is affinity chromatography purified via peptide column. (Protein A or G Sepharose)
|Homo sapiens breast cancer anti-estrogen resistance 3 (BCAR3), transcript variant 1|
|BCAR3 Antibody: Breast cancer anti-estrogen resistance 3 (BCAR3) was identified in the search for genes involved in the development of estrogen resistance. It contains a putative src homology 2 (SH2) domain and is partly homologous to the cell division cycle protein CDC48. BCAR3 is a binding partner with Cas, an adapter molecule that plays a role in cell proliferation, survival, cell adhesion, and mobility. BCAR3 functions synergistically with Cas to enhance Src activation and promote cell migration, and has been suggested to regulate Cas/Src association, Src kinase activity, and breast cancer adhesion signaling. |
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Western blot analysis of BCAR3 in mouse kidney tissue lysate with BCAR3 antibody at A) 1 and (B) 2 ug/mL.