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Home Antibody All anti-BAK1 antibodies

Anti-BAK1 Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA306175 Rabbit Polyclonal Bak Antibody 100ug $325 3-7 Days
LC400476 BAK1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenBak antibody was raised against a peptide corresponding to 13 amino acids near the amino-terminus of human Bak.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse Concentration1ug/ul
Guaranteed Application *WB, IF Suggested DilutionsWB: 1 - 2 ug/mL, ICC: 2 ug/mL
BufferPBS containing 0.02% sodium azide.
Purification Ion exchange chromatography purified

Reference Data

Target NameHomo sapiens BCL2-antagonist/killer 1 (BAK1)
Alternative NameBAK; BAK-LIKE; BCL2L7; CDN1
Database LinkNP_001179
Entrez Gene 578 Human
Entrez Gene 12018 Mouse
FunctionApoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer (reviewed in 1). The Bcl-2 family of proteins is comprised of critical regulators of apoptosis that can be divided into two classes: those that inhibit apoptosis and those that promote cell death (reviewed in 2 and 3). Bak, a pro-apoptotic Bcl-2 family member, is an oligomeric protein that localizes to the mitochondria (4,5). It is thought to share significant functional homology with Bax, another pro-apoptotic Bcl-2 family member, as disruption of bak or bax has little effect on cell death, but mice lacking both genes display multiple developmental defects and cells lacking bak and bax show decreased apoptotic capability (6,7).
Related PathwayTransmembraneStem cell - PluripotencyDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of Bak in L1210 cell lysates with Bak antibody at (A) 1 and (B) 2 ug/mL.

IF Image
Immunocytochemistry of Bak in L1210 cells with Bak antibody at 2 ug/mL.


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