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Anti-BAIAP2 TRUEMAB Antibody clone 1C10
TrueMAB Antibodies - Made against Authentic Protein Antigens
Also for BAIAP2 (NM_006340)
|Full length human recombinant protein of human BAIAP2(NP_005331) produced in HEK293 cell.|
|WB, IF, FC
||WB 1:2000, IF 1:100, FLOW 1:100,
|PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purified from mouse ascites fluids by affinity chromatography (Protein A or G Sepharose)
|Homo sapiens BAI1-associated protein 2 (BAIAP2), transcript variant 3|
|BAP2; FLAF3; IRSP53|
|The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. This protein is involved in lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms.|
Signaling by GPCR
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY BAIAP2 (RC214570, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-BAIAP2.
Anti-BAIAP2 mouse monoclonal antibody (TA503342) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY BAIAP2(RC214570).
HEK293T cells transfected with either RC214570 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-BAIAP2 antibody(TA503342), and then analyzed by flow cytometry.