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Home Antibody All anti-BAIAP2 antibodies

Anti-BAIAP2 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA302427
  • Goat Polyclonal Antibody against BAIAP2 (isoform 1)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC402587) , 20ug Explanation
100ug 325 3-7 Days
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WB(1)
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Also for BAIAP2 (NM_017450)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenPeptide with sequence C-SGSGTLVSTV, from the C Terminus of the protein sequence according to NP_059344.1.
Clone Name IsotypeGoat IgG
Species ReactivityTest: Human. Expected from seq similarity: Human, Mouse, Rat Concentration0.5 mg/ml
Guaranteed Application *WB Suggested DilutionsELISA: 1:64,000. WB 1-3µg/ml.
Predicted MW Explanation 60987Da
BufferSupplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Reference Data

Target NameHomo sapiens BAI1-associated protein 2 (BAIAP2), transcript variant 1
Alternative NameBAP2; FLAF3; IRSP53
Database LinkNP_059344
Entrez Gene 10458 Human
Entrez Gene 108100 Mouse
Entrez Gene 117542 Rat
FunctionThe protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. This protein is involved in lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Related PathwayDruggable Genome Adherens junctionRegulation of actin cytoskeleton

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
TA302427 staining (1µg/ml) of Human Brain lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

 

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