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Anti-BACE1 Antibody EPR3956
Also for BACE1 (NM_012104)
|A synthetic peptide corresponding to residues in human BACE1 was used as an immunogen.|
|Human, Mouse, Rat
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:1000 - 1:10000; IP: 1:10 - 1:100
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Tissue culture supernatant (Protein A or G Sepharose)
|Is unsuitable for Flow Cyt,ICC or IHC-P.
|Homo sapiens beta-site APP-cleaving enzyme 1 (BACE1), transcript variant a|
|ASP2; BACE; HSPC104|
|Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is BACE1. BACE1 is a member of the peptidase A1 protein family, a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi (1).|
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Western blot - BACE1 antibody [EPR3956]; All lanes : Anti-BACE1 antibody [EPR3956] at 1/1000 dilution.Lane 1 : Fetal brain lysate.Lane 2 : SH-SY5Y lysate.Lane 3 : Mouse brain lysate.Lane 4 : Rat brain lysate.Lysates/proteins at 10 µg per lane.Predicted band size : 56 kDa.