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Home Antibody All anti-BACE1 antibodies

Anti-BACE1 Antibody EPR3956

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307125
  • Rabbit monoclonal antibody against BACE1(clone EPR3956)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC402147) , 20ug
100ul 325 3-7 Days
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WB(1)
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Also for BACE1 (NM_012104)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human BACE1 was used as an immunogen.
Clone NameEPR3956 IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB Suggested DilutionsWB: 1:1000 - 1:10000; IP: 1:10 - 1:100
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt,ICC or IHC-P.

Reference Data

Target NameHomo sapiens beta-site APP-cleaving enzyme 1 (BACE1), transcript variant a
Alternative NameASP2; BACE; HSPC104
Database LinkNP_036236
FunctionCerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is BACE1. BACE1 is a member of the peptidase A1 protein family, a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi (1).
Related Pathway

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WB Image
Western blot - BACE1 antibody [EPR3956]; All lanes : Anti-BACE1 antibody [EPR3956] at 1/1000 dilution.Lane 1 : Fetal brain lysate.Lane 2 : SH-SY5Y lysate.Lane 3 : Mouse brain lysate.Lane 4 : Rat brain lysate.Lysates/proteins at 10 µg per lane.Predicted band size : 56 kDa.

 

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