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Home Antibody All anti-App antibodies

Anti-App Antibody

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA309529 Goat Polyclonal Antibody against Amyloid beta peptide (mouse) 100ug $325 3-7 Days
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WB(1)

OriGene Data

ImmunogenPeptide with sequence DAEFGHDSGFEVRHQK-C, from the N Terminus of the protein sequence according to NP_001185752.1; NP_031497.2; NP_001185753.1; NP_001185754.1; NP_001185755.1.
Clone Name Isotype
Species ReactivityTest: Mouse, Rat. Expected from seq similarity: Mouse, Rat ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 0.03-1ug/ml
BufferSupplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Reference Data

Target NameMus musculus amyloid beta (A4) precursor protein (App), transcript variant 2
Alternative NameAbeta; Abpp; Adap; Ag; betaApp; Cvap; E030013M08Rik
Database LinkNP_031497
Entrez Gene 11820 Mouse
Entrez Gene 54226 Rat
FunctionThis gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq].
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

TA309529 (0.03µg/ml) staining of Mouse Brain lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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