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Home Antibody All anti-AURKA antibodies



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TA325248 Rabbit Polyclonal Aurora Kinase (Thr288) Antibody (Phospho-specific) 100ul 325
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OriGene Data

ImmunogenThe antiserum was produced against A synthesized peptide derived from human Aurora Kinase around the phosphorylation site of Threonine 288
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1 mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 1:500-1:2000; IHC: 1:50-1:200
Predicted MW Explanation 48kDa
BufferRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide.

Reference Data

Target NameHomo sapiens aurora kinase A (AURKA), transcript variant 2
Alternative NameAIK; ARK1; AURA; AURORA2; BTAK; PPP1R47; STK15; STK6; STK7
Database LinkNP_003591
Entrez Gene 6790 Human
Entrez Gene 20878 Mouse
Entrez Gene 261730 Rat
FunctionThe protein encoded by this gene is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cells and at the spindle poles in mitosis. This gene may play a role in tumor development and progression.
Related PathwayProtein KinaseStem cell - PluripotencyDruggable Genome Oocyte meiosis

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WB Image
Western blot analysis of Aurora Kinase phosphorylation expression in serum treated 293 whole cell lysates,The lane on the left is treated with the antigen-specific peptide.


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