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Home Antibody All anti-ATP7B antibodies

Anti-ATP7B Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA301761
  • Rabbit Polyclonal Antibody against ATP7b
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC424958) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
IHC(1)
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Also for ATP7B (NM_000053)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide made to an internal sequence near the N-terminus of human ATP7b.
Clone Name IsotypeIgG
Species Reactivityhuman, mouse Concentration1 mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1: 1000
BufferTris citrate/phosphate [pH 7-8] and 0.1% sodium azide
Purification Affinity purified

Reference Data

Target NameHomo sapiens ATPase, Cu++ transporting, beta polypeptide (ATP7B), transcript variant 1
Alternative NamePWD; WC1; WD; WND
Database LinkNP_000044
Entrez Gene 540 Human
Entrez Gene 11979 Mouse
FunctionATP7b is an important protein for copper transport and elimination of excess copper from the body. ATP7b transports metals in and out of cells using ATP. There are 3 known isoforms of the ATP7b gene; A is found in the liver, kidney, and brain, the shorter form B is found in brain tissue, and the third isoform, known as WND/140 KDA is found in mitochondria. Mutations in the ATP7b gene can cause Wilson's disease, an inherited disorder causing copper poisoning in the brain and liver.
Related PathwayTransmembraneDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
ATP7b detected in 20 ug of mouse brain membrane fraction
IHC Image
Immunohistochemistry: ATP7b Antibody - Analysis of ATP7b in mouse liver using DAB with hematoxylin counterstain.

 

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