Home Antibody All anti-ATP7B antibodies
Also for ATP7B (NM_000053)
|A synthetic peptide made to an internal sequence near the N-terminus of human ATP7b.|
||WB: 1: 1000
|Tris citrate/phosphate [pH 7-8] and 0.1% sodium azide|
|Affinity purified (Protein A or G Sepharose)
|Homo sapiens ATPase, Cu++ transporting, beta polypeptide (ATP7B), transcript variant 1|
|PWD; WC1; WD; WND|
|ATP7b is an important protein for copper transport and elimination of excess copper from the body. ATP7b transports metals in and out of cells using ATP. There are 3 known isoforms of the ATP7b gene; A is found in the liver, kidney, and brain, the shorter form B is found in brain tissue, and the third isoform, known as WND/140 KDA is found in mitochondria. Mutations in the ATP7b gene can cause Wilson's disease, an inherited disorder causing copper poisoning in the brain and liver. |
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ATP7b detected in 20 ug of mouse brain membrane fraction
Immunohistochemistry: ATP7b Antibody - Analysis of ATP7b in mouse liver using DAB with hematoxylin counterstain.