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Home Antibody All anti-ATP7B antibodies

Anti-ATP7B Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA301761
  • Rabbit Polyclonal Antibody against ATP7b
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC424958) , 20ug
100ul 325 3-7 Days
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WB(1)
IHC(1)
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Also for ATP7B (NM_000053)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide made to an internal sequence near the N-terminus of human ATP7b.
Clone Name IsotypeIgG
Species Reactivityhuman, mouse Concentration1 mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1: 1000
BufferTris citrate/phosphate [pH 7-8] and 0.1% sodium azide
Purification Affinity purified

Reference Data

Target NameHomo sapiens ATPase, Cu++ transporting, beta polypeptide (ATP7B), transcript variant 1
Alternative NamePWD; WC1; WD; WND
Database LinkNP_000044
FunctionATP7b is an important protein for copper transport and elimination of excess copper from the body. ATP7b transports metals in and out of cells using ATP. There are 3 known isoforms of the ATP7b gene; A is found in the liver, kidney, and brain, the shorter form B is found in brain tissue, and the third isoform, known as WND/140 KDA is found in mitochondria. Mutations in the ATP7b gene can cause Wilson's disease, an inherited disorder causing copper poisoning in the brain and liver.
Related Pathway

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WB Image
ATP7b detected in 20 ug of mouse brain membrane fraction
IHC Image
Immunohistochemistry: ATP7b Antibody - Analysis of ATP7b in mouse liver using DAB with hematoxylin counterstain.

 

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