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Anti-ATP2A1 Antibody EPR7322
Also for ATP2A1 (NM_004320)
|A synthetic peptide corresponding to residues in human ATP2A1 was used as an immunogen.|
|Human, Mouse, Rat
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:1000 - 1:10000
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
|Tissue culture supernatant (Protein A or G Sepharose)
|Is unsuitable for IHC-P or IP.
|Homo sapiens ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 (ATP2A1), transcript variant a|
|ATP2A1 is one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and it is involved in muscular excitation and contraction. Mutations in ATP2A1 cause some autosomal recessive forms of Brody disease, characterized by increasing impairment of muscular relaxation during exercise (1).|
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Western blot - Anti-SERCA1 ATPase antibody [EPR7322]; All lanes : Anti-SERCA1 ATPase antibody [EPR7322] at 1/1000 dilution.Lane 1 : Human fetal muscle lysate.Lane 2 : Rat muscle lysate.Lane 3 : Mouse muscle lysate.Lysates/proteins at 10 µg per lane.Secondary.Goat anti-Rabbit HRP at 1/2000 dilution.Predicted band size : 110 kDa.
Other-Anti-SERCA1 ATPase antibody [EPR7322](ab129104); Equilibrium disassociation constant (KD)..