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Anti-ATIC TRUEMAB Antibody Clone 1D2
TrueMAB Antibodies - Made against Authentic Protein Antigens
Also for ATIC (NM_004044)
|Full length human recombinant protein of human ATIC(NP_004035) produced in HEK293T cell.|
|Human , Dog , Rat , Monkey , Mouse
||WB 1:500~2000, FLOW 1:100,
|PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purified from mouse ascites fluids by affinity chromatography
|Homo sapiens 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase (ATIC)|
|AICAR; AICARFT; HEL-S-70p; IMPCHASE; PURH|
Entrez Gene 471 Human
Entrez Gene 108147 Mouse
Entrez Gene 81643 Rat
Entrez Gene 488513 Dog
|This gene encodes a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N-terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C-terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA-ribosiduria. [provided by RefSeq]. |
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ATIC (RC203490, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ATIC.
Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-ATIC monoclonal antibody.
HEK293T cells transfected with either RC203490 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-ATIC antibody(TA504553), and then analyzed by flow cytometry.