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Home Antibody All anti-ATG5 antibodies

Anti-ATG5 Antibody EPR1755(2)

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SKU Description Amount Price Availability*  
TA307270
  • Rabbit monoclonal antibody against Atg5(clone EPR1755(2))
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401532) , 20ug Explanation
100ul $325 3-7 Days
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WB(1)
IHC(2)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human Atg5 was used as an immunogen.
Clone NameEPR1755(2) IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:10000; IP: 1:10 - 1:100; IHC-P: 1:100 - 1:250; ICC: 1:100 - 1:250
Predicted MW Explanation 32 kDa
BufferpH: 7.40
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt.

Reference Data

Target NameHomo sapiens autophagy related 5 (ATG5), transcript variant 1
Alternative NameAPG5; APG5-LIKE; APG5L; ASP; hAPG5
Database LinkNP_004840
Entrez Gene 9474 Human
Entrez Gene 11793 Mouse
Entrez Gene 365601 Rat
FunctionAtg5 (Autophagy protein 5) is required for autophagy. It conjugates to ATG12 and associates with isolation membrane to form cup-shaped isolation membrane and autophagosome. The conjugate detaches from the membrane immediately before or after autophagosome formation is completed. Atg5 may also play an important role in the apoptotic process, possibly within the modified cytoskeleton. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity (1).
Related PathwayDruggable Genome Regulation of autophagyRIG-I-like receptor signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - APG5L/ATG5 antibody [EPR1755(2)]; All lanes : Anti-APG5L/ATG5 antibody [EPR1755(2)] at 1/1000 dilution.Lane 1 : Raji cell lysate.Lane 2 : HeLa cell lysate.Lane 3 : HT-1080 cell lysate.Lane 4 : Human fetal kidney cell lysate.Lane 5 : C6 cell lysate.Lane 6 : Raw264.7 cell lysate.Lane 7 : PC-12 cell lysate.Lane 8 : NIH3T3 cell lysate.Lysates/proteins at 10 ug per lane.Predicted band size : 32 kDa.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - APG5L/ATG5 antibody [EPR1755(2)]; TA307270, at 1/100 dilution, staining APG5L/ATG5 in paraffin-embedded Human hepatocellular carcinoma tissue by Immunohistochemistry.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - APG5L/ATG5 antibody [EPR1755(2)]; TA307270, at 1/100 dilution, staining APG5L/ATG5 in paraffin-embedded Human ovarian adenocarcinoma tissue by Immunohistochemistry.
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