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Anti-ASPSCR1 Antibody EPR8615
Also for ASPSCR1 (NM_024083)
|A synthetic peptide corresponding to residues in human Tug was used as an immunogen.|
|Human, Mouse, Rat
||0.5~1.0 mg/ml (Lot Dependent)
|WB, ASSAY, IHC
||WB: 1:10000 - 1:50000; IP: 1:10 - 1:100; IHC-P: 1:100 - 1:250
Preservative: 0.01% Sodium azide
Constituents: 48% PBS, 50% Glycerol, 0.05% BSA
|Tissue culture supernatant (Protein A or G Sepharose)
|Is unsuitable for Flow Cyt or ICC.
|Homo sapiens alveolar soft part sarcoma chromosome region, candidate 1 (ASPSCR1), transcript variant 1|
|ASPCR1; ASPL; ASPS; RCC17; TUG; UBXD9; UBXN9|
|Tug contains a UBX domain and interacts with glucose transporter type 4 (GLUT4). It is a tether, which sequesters GLUT4 in intracellular vesicles in muscle and fat cells in the absence of insulin, and redistributes GLUT4 to the plasma membrane within minutes of insulin stimulation. Translocation with transcription factor TFE3 results in a ASPSCR1-TFE3 fusion protein in alveolar soft part sarcoma and in renal cell carcinomas (1). |
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Western blot - Anti-TUG antibody [EPR8615]; All lanes : Anti-TUG antibody [EPR8615] at 1/10000 dilution.Lane 1 : K562 cell lysate.Lane 2 : 293T cell lysate.Lane 3 : SW480 cell lysate.Lysates/proteins at 10 µg per lane.Predicted band size : 60 kDa.
Other-Anti-TUG antibody [EPR8615](ab131237); Equilibrium disassociation constant (KD)..
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TUG antibody [EPR8615]; ab131237, at 1/100, staining TUG in Formalin-fixed, Paraffin-embedded Human colon tissue by Immunohistochemistry.