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Anti-APP TRUEMAB Antibody Clone 7B8

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA505055
  • APP (Amyloid beta precursor protein) mouse monoclonal antibody, Clone 7B8
  • FREE positive control: HEK293T cell transient overexpression lysate (LC424694) , 20ug
100ul 325 In Stock
CF505055
  • Carrier-free (BSA/glycerol-free) APP mouse monoclonal antibody,clone 7B8
100ug $450 3 Days
Conjugation is available for this antibody: choose conjugation type
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WB(1)
IHC(9)

OriGene Data

ImmunogenFull length human recombinant protein of human APP(NP_000475) produced in HEK293T cell.
Clone NameClone 7B8 IsotypeIgG2a
Species ReactivityHuman Concentration1.00 mg/ml
Guaranteed Application *WB, IHC Suggested Dilutions WB 1:2000, IHC 1:150,
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens amyloid beta (A4) precursor protein (APP), transcript variant 1
Alternative NameAAA; ABETA; ABPP; AD1; APPI; CTFgamma; CVAP; PN-II; PN2
Database LinkNP_000475
FunctionThis gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq].
Related Pathway
Delta-Notch Signaling Pathway
Hemostasis

* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY APP (RC221339, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-APP.
IHC Image
Immunohistochemical staining of paraffin-embedded Human breast tissue using anti-APP mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA505055)
IHC Image
Immunohistochemical staining of paraffin-embedded Human Kidney tissue using anti-APP mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA505055)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human kidney tissue using anti-APP mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA505055)
IHC Image
Immunohistochemical staining of paraffin-embedded Human liver tissue using anti-APP mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA505055)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human liver tissue using anti-APP mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA505055)
IHC Image
Immunohistochemical staining of paraffin-embedded Human pancreas tissue using anti-APP mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA505055)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human thyroid tissue using anti-APP mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA505055)
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-APP mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA505055)
IHC Image
Immunohistochemical staining of paraffin-embedded Human prostate tissue using anti-APP mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA505055)

 

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