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Home Antibody All anti-ANAPC13 antibodies

Anti-ANAPC13 Antibody Polyclonal

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA319874
  • Rabbit Polyclonal APC13 Antibody
100ug 325 3-7 Days
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WB(1)
IF(1)
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Also for ANAPC13 (NM_015391)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenAPC13 antibody was raised against a 17 amino acid synthetic peptide near the center of human APC13.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IF Suggested DilutionsWB: 1 ug/ml, IF: 20 ug/ml
BufferAPC13 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification APC13 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens anaphase promoting complex subunit 13 (ANAPC13), transcript variant 1
Alternative NameAPC13; SWM1
Database LinkNP_056206
FunctionAPC13 Antibody: Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis. APC13 is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence. The individual APC/C components mRNA and protein levels are expressed at approximately the same levels in most tissues and cell lines, suggesting that they perform their functions as part of a complex. APC13 promotes the stable association of APC3/Cdc27 and APC6/Cdc16 with the APC/C.
Related Pathway
Cell cycle

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of APC13 in Jurkat cell tissue lysate with APC13 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.
IF Image
Immunofluorescence of APC13 in Jurkat cells with APC13 antibody at 20 ug/mL.

 

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