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Home All anti-AKT1 antibodies
Anti-AKT1 Antibody Y90
TrueMAB™ Antibodies - Made against Authentic Protein Antigens
* Buy one primary antibody, get 50% off a GAPDH loading control antibody.
Also for AKT1 (NM_001014432)
OriGene Data
| A synthetic peptide corresponding to residues surrounding ATP binding site of human Akt1 was used as immunogen. Predicted to cross-react with mouse, rat and bovine, based on sequence homology. |
| Y90 |
Rabbit IgG |
| Human, Mouse |
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| WB |
WB: 1:1,000 |
| 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
| (Protein A or G Sepharose) |
Reference Data
| Homo sapiens v-akt murine thymoma viral oncogene homolog 1 (AKT1), transcript variant 2 |
| AKT; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA |
| NP_001014432 |
| The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq]. |
Apoptosis Delta-Notch Signaling Pathway EGFR1 Signaling Pathway Focal Adhesion Hemostasis Jak-STAT signaling pathway MAPK signaling pathway Signaling by GPCR Toll-like receptor signaling pathway Wnt Signaling Pathway |
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* OriGene provides validated application data and protocol, with money back guarantee.
WB Image
Western blot analysis on MCF-7 cell lysate using anti- Akt1/PKBa RabMAb (TA303386); dilution 1:1,000.
Conjugation Services
OriGene provides conjugation services of TrueMAB antibodies with the following molecules:
- HRP
- Biotin
- PE
- FITC
- DyLight® 488
- DyLight® 550
- DyLight® 594
- DyLight® 633
* DyLight is a trademark of Thermo-Fisher Scientific
Bulk Order
OriGene offers bulk sizes of TrueMAB antibodies in both the BSA/glycerol formulation and the carrier-free (BSA/glycerol-free) formulation.
Contact us with your conjugation/bulk request: antibody@origene.com or 888-267-4436 (Tech Support)
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