Home Antibody All anti-AKR1C1 antibodies
Also for AKR1C1 (NM_001353)
|Recombinant protein fragment contain a sequence corresponding to a region within amino acids 22 and 218 of Human AKR1C1|
|WB, IHC, IF
||WB:1:500-1:3000; IHC:1:500; IF:1:100-1:500;
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Homo sapiens aldo-keto reductase family 1, member C1 (AKR1C1)|
|2-ALPHA-HSD; 20-ALPHA-HSD; C9; DD1; DD1/DD2; DDH; DDH1; H-37; HAKRC; HBAB; MBAB|
Entrez Gene 1645 Human
|This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. [provided by RefSeq]|
|Druggable Genome Metabolism of xenobiotics by cytochrome P450|
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Sample(30 ug whole cell lysate) A:Raji (anti-AKR1C1 antibody diluted at 1:1000)
Immunohistochemical analysis of paraffin-embedded MDA-MB-468 xenograft , using AKR1C1(anti-AKR1C1 antibody) antibody at 1:500 dilution.
Immunofluorescence analysis of methanol-fixed A431, using AKR1C1(anti-AKR1C1 antibody) antibody at 1:200 dilution.