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Home Antibody All anti-AKR1C1 antibodies

Anti-AKR1C1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308032
  • Rabbit Polyclonal antibody to AKR1C1 (aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase))
  • FREE positive control: HEK293T cell transient overexpression lysate (LC419968) , 20ug
100ul $325 3-7 Days
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WB(1)
IHC(1)
IF(1)
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Also for AKR1C1 (NM_001353)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenRecombinant protein fragment contain a sequence corresponding to a region within amino acids 22 and 218 of Human AKR1C1
Clone Name IsotypeIgG
Species ReactivityHuman Concentration1mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB:1:500-1:3000; IHC:1:500; IF:1:100-1:500;
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.

Reference Data

Target NameHomo sapiens aldo-keto reductase family 1, member C1 (AKR1C1)
Alternative Name2-ALPHA-HSD; 20-ALPHA-HSD; C9; DD1; DD1/DD2; DDH; DDH1; H-37; HAKRC; HBAB; MBAB
Database LinkNP_001344
FunctionThis gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. [provided by RefSeq]
Related Pathway

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WB Image
Sample(30 ug whole cell lysate) A:Raji (anti-AKR1C1 antibody diluted at 1:1000)
IHC Image
Immunohistochemical analysis of paraffin-embedded MDA-MB-468 xenograft , using AKR1C1(anti-AKR1C1 antibody) antibody at 1:500 dilution.
IF Image
Immunofluorescence analysis of methanol-fixed A431, using AKR1C1(anti-AKR1C1 antibody) antibody at 1:200 dilution.

 

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