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Home Antibody All anti-AICDA antibodies

Anti-AICDA Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306117
  • Rabbit Polyclonal AID Antibody
  • FREE positive control: HEK293T cell transient overexpression lysate (LC412399) , 20ug
100ug $325 In Stock
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WB(1)
IF(1)

OriGene Data

ImmunogenAID antibody was raised against a peptide corresponding to 14 amino acids near the carboxy-terminus of human AID.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, IF Suggested DilutionsELISA, WB: 2 ug/ml, ICC: 10 ug/ml, IF: 20 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens activation-induced cytidine deaminase (AICDA)
Alternative NameAID; ARP2; CDA2; HEL-S-284; HIGM2
Database LinkNP_065712
FunctionActivation-induced cytidine deaminase (AID) was initially discovered as a homolog of the apolipoprotein B RNA-editing cytidine deaminase 1 (APOBEC1) that showed cytidine deaminase properties in stimulated B cell lines (1). It is necessary for somatic hypermutation and class switch recombination in B cells (2), but inappropriate or dysregulated expression AID is often found in tumors and B cell neoplasms (2,3). Although it is structurally and functionally similar to the APOBEC proteins (reviewed in 4), it appears unlikely that AID deaminates dC to dU residues in HIV cDNA as does APOBEC3G (5).
Related Pathway

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WB Image
Western blot analysis of AID in Ramos whole cell lysate with AID antibody at 2 ug/mL in either the (A) absence or (B) presence of blocking peptide.
IF Image
Immunocytochemistry of AID in Ramos cells with Ramos antibody at 10 ug/mL.

 

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