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Home Antibody All anti-AGTR2 antibodies

Anti-AGTR2 Antibody

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA306840 Rabbit Polyclonal AGTR2 Antibody 100ug $325 3-7 Days
LC400227 AGTR2 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(1)
IHC(1)

OriGene Data

ImmunogenAGTR2 antibody was raised against a 16 amino acid peptide from near the center of human AGTR2.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC Suggested DilutionsWB: 0.5 - 1 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens angiotensin II receptor, type 2 (AGTR2)
Alternative NameAT2; ATGR2; MRX88
Database LinkNP_000677
Entrez Gene 186 Human
Entrez Gene 11609 Mouse
Entrez Gene 24182 Rat
FunctionAngiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion that acts through at least two types of receptors, AGTR1 and AGTR2. It is an important effector controlling blood pressure and volume in the cardiovascular system and plays a major role in the development of the mammalian kidney and urinary tract. Like AGTR1, AGTR2 is a seven transmembrane G protein-coupled receptor (GPCR), but AGTR2 does not demonstrate most of the classic features of GPCR signaling. AGTR2 is involved in a wide range of activities, including the induction of neurite outgrowth and the inhibition of cellular proliferation, in addition to the known function of mediation of vasoconstriction.
Related PathwayGPCRTransmembraneDruggable Genome Neuroactive ligand-receptor interactionRenin-angiotensin system

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of AGTR2 in mouse liver tissue lysate with AGTR2 antibody at 0.5 µg/ml.
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Immunohistochemistry of AGTR2 in rat liver tissue with AGTR2 antibody at 5 ug/ml.
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