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Home Antibody All anti-ACSL1 antibodies

Anti-ACSL1 Antibody Polyclonal


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA319649 Rabbit Polyclonal ACSL1 Antibody 100ug $325 3-7 Days
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OriGene Data

ImmunogenRabbit polyclonal ACSL1 antibody was raised against an 18 amino acid peptide near the center of human ACSL1.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IF Suggested DilutionsWB: 1 - 2 ug/mL, IF: 20 ug/mL
Predicted MW Explanation 77 kDa
BufferACSL1 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification ACSL1 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens acyl-CoA synthetase long-chain family member 1 (ACSL1), transcript variant 1
Alternative NameACS1; FACL1; FACL2; LACS; LACS1; LACS2
Database LinkNP_001986
Entrez Gene 2180 Human
Entrez Gene 14081 Mouse
Entrez Gene 25288 Rat
FunctionACSL1 Antibody: Long-chain acyl coenzyme A synthetase 1 (ACSL1) catalyzes the synthesis of acyl-CoA from long-chain fatty acids in an ATP-dependent manner. ACSL1 is a member of a family of long-chain acyl-CoA synthetases which differ in substrate preference, tissue expression, and subcellular localization. In mouse, ASCL1 is the major acyl-CoA enzyme in the heart, providing 60-90% of heart ATP. Loss of ASCL1 either globally or in heart ventricles resulted in impaired fatty acid oxidation, activation of the mammalian target of rapamycin (mTOR), and cardiac hypertrophy.
Related PathwayTransmembrane Fatty acid metabolismMetabolic pathwaysPPAR signaling pathwayAdipocytokine signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of ACSL1 in human lung tissue lysate with ACSL1 antibody at (A) 1 and (B) 2 ug/mL.

IF Image
Immunofluorescence of ASCL1 in human lung tissue with ASCL1 antibody at 20 ug/mL.


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