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Home Antibody All anti-ACHE antibodies

Anti-ACHE Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308776
  • Rabbit polyclonal antibody to AChE (acetylcholinesterase (Yt blood group))
  • FREE positive control: HEK293T cell transient overexpression lysate (LC425009) , 20ug
100ul 325 3-7 Days
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WB(1)
IF(1)

OriGene Data

ImmunogenRecombinant protein fragment contain a sequence corresponding to a region within amino acids 406 and 610 of Human ACHE
Clone Name IsotypeIgG
Species ReactivityHuman Concentration1mg/ml
Guaranteed Application *WB, IF Suggested DilutionsWB:1:500-1:3000; IF:1:100-1:200;
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.

Reference Data

Target NameHomo sapiens acetylcholinesterase (Yt blood group) (ACHE), transcript variant E4-E6
Alternative NameACEE; ARACHE; N-ACHE; YT
Database LinkNP_000656
FunctionAcetylcholinesterase hydrolyzes the neurotransmitter, acetylcholine at neuromuscular junctions and brain cholinergic synapses, and thus terminates signal transmission. It is also found on the red blood cell membranes, where it constitutes the Yt blood group antigen. Acetylcholinesterase exists in multiple molecular forms which possess similar catalytic properties, but differ in their oligomeric assembly and mode of cell attachment to the cell surface. It is encoded by the single ACHE gene, and the structural diversity in the gene products arises from alternative mRNA splicing, and post-translational associations of catalytic and structural subunits. The major form of acetylcholinesterase found in brain, muscle and other tissues is the hydrophilic species, which forms disulfide-linked oligomers with collagenous, or lipid-containing structural subunits. The other, alternatively spliced form, expressed primarily in the erythroid tissues, differs at the C-terminal end, and contains a cleavable hydrophobic peptide with a GPI-anchor site. It associates with the membranes through the phosphoinositide (PI) moieties added post-translationally. [provided by RefSeq]
Related Pathway

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WB Image
Sample (30 ug of whole cell lysate) A: Raji (anti-ACHE antibody diluted at 1:1000)
IF Image
Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using AChE(anti-ACHE antibody) antibody at 1:200 dilution.

 

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