Anti-ACHE Antibody,

Also for ACHE (NM_000665)

OriGene Data

Immunogen	Recombinant protein fragment contain a sequence corresponding to a region within amino acids 406 and 610 of Human ACHE
Clone Name		Isotype	IgG
Species Reactivity	Human	Concentration	1mg/ml
Guaranteed Application *	WB, IF	Suggested Dilutions	WB:1:500-1:3000; IF:1:100-1:200;
Buffer	0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification	Purified by antigen-affinity chromatography. (Protein A or G Sepharose)

Reference Data

Target Name	Homo sapiens acetylcholinesterase (ACHE), transcript variant E4-E6
Alternative Name	ACEE; ARACHE; N-ACHE; YT
Database Link	NP_000656
Function	Acetylcholinesterase hydrolyzes the neurotransmitter, acetylcholine at neuromuscular junctions and brain cholinergic synapses, and thus terminates signal transmission. It is also found on the red blood cell membranes, where it constitutes the Yt blood group antigen. Acetylcholinesterase exists in multiple molecular forms which possess similar catalytic properties, but differ in their oligomeric assembly and mode of cell attachment to the cell surface. It is encoded by the single ACHE gene, and the structural diversity in the gene products arises from alternative mRNA splicing, and post-translational associations of catalytic and structural subunits. The major form of acetylcholinesterase found in brain, muscle and other tissues is the hydrophilic species, which forms disulfide-linked oligomers with collagenous, or lipid-containing structural subunits. The other, alternatively spliced form, expressed primarily in the erythroid tissues, differs at the C-terminal end, and contains a cleavable hydrophobic peptide with a GPI-anchor site. It associates with the membranes through the phosphoinositide (PI) moieties added post-translationally. [provided by RefSeq]
Related Pathway

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WB Image

Sample (30 ug of whole cell lysate) A: Raji (anti-ACHE antibody diluted at 1:1000)

IF Image

Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using AChE(anti-ACHE antibody) antibody at 1:200 dilution.

Conjugation Services
OriGene provides conjugation services of TrueMAB antibodies with the following molecules:

HRP
Biotin
PE
FITC
DyLight® 488
DyLight® 550
DyLight® 594
DyLight® 633

* DyLight is a trademark of Thermo-Fisher Scientific

Bulk Order
OriGene offers bulk sizes of TrueMAB antibodies in both the BSA/glycerol formulation and the carrier-free (BSA/glycerol-free) formulation.

Anti-ACHE Antibody

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

OriGene Data

Reference Data