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Home Antibody All anti-ABL2 antibodies

Anti-ABL2 GAT Antibody Polyclonal

Generated by Genomic Immunization


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA590236 Rabbit Polyclonal ABL2 Antibody 100ug $325 In Stock
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OriGene Data

ImmunogenDNA immunization. This antibody is specific for the Middle Region of the target protein.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman Concentration0.88mg/ml
Guaranteed Application *WB, ELISA, IHC, IF Suggested Dilutions WB 1:5000~20000,ELISA 1:100-1:2000
Buffer20 mM Potassium Phosphate, 150 mM Sodium Chloride, pH 7.0
Purification The fragment used for DNA immunization was expressed in E.coli and the purified protein fragment was used for affinity purification of the antibody.
Note This antibody was generated by SDIX's Genomic Antibody Technology ® (GAT). Learn about GAT

Reference Data

Target NameHomo sapiens ABL proto-oncogene 2, non-receptor tyrosine kinase (ABL2), transcript variant b
Alternative NameABLL; ARG
Database LinkNP_009298
Entrez Gene 27 Human
FunctionThis gene encodes a member of the Abelson family of nonreceptor tyrosine protein kinase. The protein is highly similar to the ABL1 protein, including the tyrosine kinase, SH2 and SH3 domains, and has a role in cytoskeletal rearrangements by its C-terminal F-actin- and microtubule-binding sequences. This gene is expressed in both normal and tumor cells, and is involved in translocation with the ETV6 gene in leukemia. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq]
Related PathwayProtein KinaseDruggable Genome ErbB signaling pathwayViral myocarditis

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* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ABL2 (RC213232, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ABL2.
Western Blot: ABL2 Antibody - Lane 1, Marker: 250, 130, 95, 72, 55, 36, 28, 17, 11 Ln 2, RT-4 Ln 3, U-251MG sp Ln 4, Human Plasma Ln 5, Liver Ln 6, Tonsil, Target weight: 128, 116, 110 (splice variants) Validation score: 2.
ELISA: ABL2 Antibody
Immunohistochemical staining of human cerebral cortex shows strong nuclear positivity in neuronal and glial cells. Antibody dilution: 1:350. Image and statement courtesy of the Human Protein Atlas (HPA).
Immunofluorescent staining of human cell line U-251 MG shows positivity in nucleus but excluded from the nucleoli. Antibody dilution: 1:87. Image and statement courtesy of the Human Protein Atlas (HPA).


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