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Home Antibody All anti-ABCB1 antibodies

Anti-ABCB1 TRUEMAB Antibody Clone 5B3

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA801055
  • ABCB1 (P Glycoprotein) mouse monoclonal antibody, Clone 5B3
100ul 325 In Stock
CF801055
  • Carrier-free (BSA/glycerol-free) ABCB1 mouse monoclonal antibody,clone 5B3
100ug $450 3 Days
Conjugation is available for this antibody: choose conjugation type
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IHC(5)
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Also for ABCB1 (NM_000927)
cDNA Clone shRNA/siRNA Primer Pair Protein Antibody

OriGene Data

ImmunogenHuman recombinant protein fragment corresponding to amino acids 995-1280 of human ABCB1 (NP_000918) produced in SF9 cell.
Clone NameClone 5B3 IsotypeIgG2a
Species ReactivityHuman Concentration1 mg/ml
Guaranteed Application *IHC Suggested Dilutions IHC 1:150,
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens ATP-binding cassette, sub-family B (MDR/TAP), member 1 (ABCB1)
Alternative NameABC20; CD243; CLCS; GP170; MDR1; P-GP; PGY1
Database LinkNP_000918
Entrez Gene 5243 Human
FunctionThe membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier. [provided by RefSeq, Jul 2008].
Related PathwayES Cell Differentiation/IPSTransmembraneDruggable Genome ABC transporters

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

IHC Image
Immunohistochemical staining of paraffin-embedded Human Kidney tissue using anti-ABCB1 mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA801055)
IHC Image
Immunohistochemical staining of paraffin-embedded Human thyroid tissue using anti-ABCB1 mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA801055)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human prostate tissue using anti-ABCB1 mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA801055)
IHC Image
Immunohistochemical staining of paraffin-embedded Human bladder tissue using anti-ABCB1 mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA801055)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human bladder tissue using anti-ABCB1 mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA801055)

 

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