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Webinar on Cancer Biomarker
Cancer Biomarker Webinar

OriGene TissueScan in recent publications
Proteomic Analysis of Temporally Stimulated Ovarian Cancer Cells for Biomarker Discovery Mol. Cell. Proteomics, Feb 2013; 12: 356 - 368. [adenocarcinoma tissue sections]
Matrix Rigidity Activates Wnt Signaling through Down-regulation of Dickkopf-1 Protein J. Biol. Chem., Jan 2013; 288: 141 - 151. [Ovarian carcinoma tissue]
Broad Cross-Presentation of the Hematopoietically Derived PR1 Antigen on Solid Tumors Leads to Susceptibility to PR1-Targeted Immunotherapy J. Immunol., Dec 2012; 189: 5476 - 5484. [Breast Tumor Tissue FFPE]
Role of Sonic Hedgehog in idiopathic pulmonary fibrosis Am J Physiol Lung Cell Mol Physiol, Dec 2012; 303: L978 - L990. [Human Lung total rna]

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Advanced Tools for Cancer Biomarker Discovery and Validation

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As a gene-centric company, OriGene has developed unique technologies and products for cancer biomarker discovery and validation

  1. Most comprehensive human cancer tissue biorepository
    • >140,000 tissue collections
    • Collected under strict IRB and ethical consenting practices
    • Annotated with associated clinical data
  2. TissueScan Cancer cDNA arrays for qPCR – mRNA expression profiling
    • Panels of normalized cDNA prepared from tumor tissues, ready for qPCR
    • Broad tumor coverage – Multiple panels for breast, colon, lung, ovarian, and prostate cancers
    • Convenient and fast – qPCR ready format; results in less than 2 hours.
  3. ProteoScan Cancer Lysate Arrays – protein expression profiling
    • High-density reverse-phase protein arrays (RPPA) spotted with cancer and normal tissue lysates
    • 432 tissue lysates from pathologist-verified normal and cancer specimens
    • 11 cancers represented (25 cancer samples +15 normal samples per cancer type)
  4. Cancer-pathway specific qPCR primer Panels
    • 21 pre-designed key cancer pathways
    • qPCR screening-ready format
    • Custom panels available

 

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9620 Medical Center Dr., Suite 200, Rockville, MD 20850 • 1.888.267.4436

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