OriGene - Il12a (NM_053390) Human ORF cDNA Clone

Western Blot Validated

TrueORF Data for RR210914

Vector:	pCMV6-Entry Change vector?	Tag: C-terminal Myc-DDK	Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Sequence Data:	ORF Nucleotide Sequence CHROMATOGRAMS	ORF Size: 648 bp Predicted Protein MW: kDa
Restriction Sites:	SgfI-MluI Cloning Scheme for this gene Plasmid Map
OTI Annotation:	This clone was engineered to express the complete ORF with an expression tag.
OTI Disclaimer:	The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components:	The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Protein Families:
Protein Pathways:

* The lysates used for this WB picture contain the overexpressed empty vector or the Myc-DDK tagged ORF clone.

Reference Data

RefSeq: NM_053390.1, NP_445842	RefSeq Size: 793	RefSeq ORF: 648
Synonyms :
LocusID: 84405	Cytogenetic: 2q31
Summary: mouse homolog is a subunit of heteromeric cytokine interleukin 12; loss of function is associated with experimental autoimmune encephalomyelitis [RGD, Feb 2006].

ORF Clones Citations:

Solute Carrier 11A1 Is Expressed by Innate Lymphocytes and Augments Their Activation, Jodi F. Hedges, Emily Kimmel, Deann T. Snyder, Maria Jerome, and Mark A. Jutila, J. Immunol., Apr 2013; 190: 4263 - 4273. [SLC11A1]

A common polymorphism in the LDL receptor gene has multiple effects on LDL receptor function, Feng Gao, Hansel E. Ihn, Marisa W. Medina, and Ronald M. Krauss, Hum. Mol. Genet., Apr 2013; 22: 1424 - 1431. [LDLR]

RNA elements directing in vivo assembly of the 7SK/MePCE/Larp7 transcriptional regulatory snRNP, Lisa Muniz, Sylvain Egloff, and Tamás Kiss, Nucleic Acids Res., Apr 2013; 41: 4686 - 4698. [MEPCE ]

Structural basis for angiopoietin-1–mediated signaling initiation, Xuehong Yu, Tom C. M. Seegar, Annamarie C. Dalton, Dorothea Tzvetkova-Robev, Yehuda Goldgur, Kanagalaghatta R. Rajashankar, Dimitar B. Nikolov, and William A. Barton, PNAS, Apr 2013; 110: 7205 - 7210. [ANGPT1]

Inverted Formin 2 Regulates Actin Dynamics by Antagonizing Rho/Diaphanous-related Formin Signaling, Hua Sun, Johannes Schlondorff, Henry N. Higgs, and Martin R. Pollak, J. Am. Soc. Nephrol., Apr 2013; 10.1681/ASN.2012080834. [INF2]

MASL1 induces erythroid differentiation in human erythropoietin-dependent CD34+ cells through the Raf/MEK/ERK pathway, Chutima Kumkhaek, Wulin Aerbajinai, Wenli Liu, Jianqiong Zhu, Naoya Uchida, Roger Kurlander, Matthew M. Hsieh, John F. Tisdale, and Griffin P. Rodgers, Blood, Apr 2013; 121: 3216 - 3227. [MFHAS1 ]

Proximal tubule-dominant transfer of AT1a receptors induces blood pressure responses to intracellular angiotensin II in AT1a receptor-deficient mice, Xiao C. Li and Jia L. Zhuo, Am J Physiol Regulatory Integrative Comp Physiol, Apr 2013; 304: R588 - R598. [AGTR1A ]

DCNL1 Functions as a Substrate Sensor and Activator of Cullin 2-RING Ligase, Pardeep Heir, Roxana I. Sufan, Samantha N. Greer, Betty P. Poon, Jeffrey E. Lee, and Michael Ohh, Mol. Cell. Biol., Apr 2013; 33: 1621 - 1631. [DCNL1]

More TrueClone Citations >>

Il12a Human Clones

SKU	Description	Amount	Price	Shipping
SC124111	Homo sapiens interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35) (IL12A) as transfection-ready DNA	10 ug	$380	5 weeks
RC211224	Myc-DDK-tagged ORF clone of Homo sapiens interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35) (IL12A) as transfection-ready DNA	10 ug	$380	Next day
RC228006	Myc-DDK-tagged ORF clone of Homo sapiens interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35) (IL12A) as transfection-ready DNA	10 ug	$380	5 weeks
RG228006	GFP-tagged ORF clone of Homo sapiens interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35) (IL12A) as transfection-ready DNA	10 ug	$420	3 weeks
RC211224L1	Lenti ORF clone of Human interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35) (IL12A) , Myc-DDK-tagged	10 ug	$750	2 weeks
RC228006L1	Lenti ORF clone of Human interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35) (IL12A) , Myc-DDK-tagged	10 ug	$750	2 weeks
RC211224L2	Lenti ORF clone of Human interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35) (IL12A), mGFP tagged	10 ug	$830	2 weeks
RC228006L2	Lenti ORF clone of Human interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35) (IL12A), mGFP tagged	10 ug	$830	2 weeks
RG211224	GFP-tagged ORF clone of Homo sapiens interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35) (IL12A) as transfection-ready DNA	10 ug	$420	Next day
RC511224	Myc-DDK-tagged ORF clone of Homo sapiens interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35) (IL12A) as 200 ug transfection-ready DNA	10 ug	$500	2~3 weeks weeks

Il12a Mouse Clones

SKU	Description	Amount	Price	Shipping
MC208768	Mus musculus interleukin 12a (Il12a), transcript variant 2 as transfection-ready DNA	10 ug	$380	Next day
MC208769	Mus musculus interleukin 12a (Il12a), transcript variant 1 as transfection-ready DNA	10 ug	$380	Next day
MR225608	Myc-DDK-tagged ORF clone of Mus musculus interleukin 12a (Il12a), transcript variant 2 as transfection-ready DNA	10 ug	$380	3 weeks
MR225609	Myc-DDK-tagged ORF clone of Mus musculus interleukin 12a (Il12a), transcript variant 1 as transfection-ready DNA	10 ug	$380	3 weeks
MG225608	GFP-tagged ORF clone of Mus musculus interleukin 12a (Il12a) transcript variant 2 as transfection-ready DNA	10 ug	$420	3 weeks
MG225609	GFP-tagged ORF clone of Mus musculus interleukin 12a (Il12a) transcript variant 1 as transfection-ready DNA	10 ug	$420	Next day

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Il12a (NM_053390) Rat cDNA ORF Clone

Western Blot Validated

ORF Clones Citations:

Il12a Human Clones

Il12a Mouse Clones

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