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Home Recombinant Human Proteins All ANGPT1 Proteins

ANGPT1 (NM_001146) Purified Human Protein

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Cat. No. Description Datasheet Price Availability*  
TP723011 Purified recombinant protein of Human angiopoietin 1 (ANGPT1), transcript variant 1., 20 ug (Larger pack size?) 399
$239
2 Weeks
TA150088 Clone OTI2B5, Anti-His mouse monoclonal antibody $248 In Stock
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OriGene Data
Species:Human Expression Host:HeLa cells
Expression cDNA Clone or AA Sequence
SNQRRSPENSGRRYNRIQHGQCAYTFILPEHDGNCRESTTDQYNTNALQRDAPHVEPDFSSQKLQHLEHVMENYTQWLQKLENYIVENMKSEMAQIQQNAVQNHTATMLEIGTSLLSQTAEQTRKLTDVETQVLNQTSRLEIQLLENSLSTYKLEKQLLQQTNEILKIHEKNSLLEHKILEMEGKHKEELDTLKEEKENLQGLVTRQTYIIQELEKQLNRATTNNSVLQKQQLELMDTVHNLVNLCTKEGVLLKGGKREEEKPFRDCADVYQAGFNKSGIYTIYINNMPEPKKVFCNMDVNGGGWTVIQHREDGSLDFQRGWKEYKMGFGNPSGEYWLGNEFIFAITSQRQYMLRIELMDWEGNRAYSQYDRFHIGNEKQNYRLYLKGHTGTAGKQSSLILHGADFSTKDADNDNCMCKCALMLTGGWWFDACGPSNLNGMFYTAGQNHGKLNGIKWHYFKGPSYSLRSTTMMIRPLDFHHHHHH
Tag:C-terminal His Predicted MW:57.3
Purity:>95% as determined by SDS-PAGE and Coomassie blue staining
Concentration:Resuspend the protein in the desired concentration in proper buffer
Buffer:Lyophilized from a 0.2 µM filtered solution of 20mM phosphate buffer,100mM NaCl, pH 7.2
Endotoxin: Endotoxin level is <0.1 ng/µg of protein (<1EU/µg).
BioActivity: Determined by the dose-dependent stimulation of the proliferation of human umbilical vein endothelial cells (HUVEC).
Protein Families: Secreted ProteinES Cell Differentiation/IPSDruggable Genome
Protein Pathways:
Protein Data
Protein Image
 

Reference Data
RefSeq: NP_001137 RefSeq Size: 4338 RefSeq ORF: 1494
LocusID: 284 Cytogenetic: 8q23.1  
Synonyms : AGP1; AGPT; ANG1
Summary: This gene encodes a secreted glycoprotein that belongs to the angiopoietin family. Members of this family play important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme and inhibits endothelial permeability. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Sep 2015].
*: Inventory for certain proteins may be limited due to low expression level. Delivery time may vary from web posted schedule. Contact techsupport@origene.com for specific inventory information
**: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich

 

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