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Home Recombinant Human Proteins All GRB2 Proteins

GRB2 (NM_002086) Purified Human Protein

Specifications Citations Customer Service Product Documents
Cat. No. Description Datasheet Price Availability*  
TP720535 Recombinant protein of human growth factor receptor-bound protein 2 (GRB2), transcript variant 1, 10 ug (Larger pack size?) $299 5 Days
TA300457 Rabbit Monoclonal Antibody against GRB2 (Clone Y237) $325 3-7 Days
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OriGene Data
Species:Human Expression Host:E. coli
Expression cDNA Clone or AA Sequence
A DNA sequence from TrueORF clone, RC200469, encoding the full length polypeptide (Met1-Val217) of human GRB2
Tag:C-terminal HIS Predicted MW:26.3 kDa
Purity:>95% as determined by SDS-PAGE and Coomassie blue staining
Concentration:Resuspend the protein to the desired concentration in proper buffer.
Buffer:Lyophilized from a 0.2 µM filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0. Stable for at least 6 months from date of receipt under proper storage and handling conditions.
Endotoxin: < 0.1 EU per µg protein as determined by LAL test
Protein Families: Druggable Genome
Protein Pathways: MAPK signaling pathwayErbB signaling pathwayChemokine signaling pathwayDorso-ventral axis formationFocal adhesionGap junctionMore Pathways >>
Protein Data
Protein Image
 

Reference Data
RefSeq: NP_002077 RefSeq Size: 3317 RefSeq ORF: 651
LocusID: 2885 Cytogenetic: 17q25.1  
Synonyms : ASH; EGFRBP-GRB2; Grb3-3; MST084; MSTP084; NCKAP2
Summary: Isoform 2 does not bind to phosphorylated epidermal growth factor receptor (EGFR) but inhibits EGF-induced transactivation of a RAS-responsive element. Isoform 2 acts as a dominant negative protein over GRB2 and by suppressing proliferative signals, may trigger active programmed cell death. [UniProtKB/Swiss-Prot Function]
*: Inventory for certain proteins may be limited due to low expression level. Delivery time may vary from web posted schedule. Contact techsupport@origene.com for specific inventory information
**: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich

 

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