AOC2 (NM_009590) Purified Human Protein

Species: Human Expression Host: Human 293HEK cells Expression cDNA Clone and Sequence Recombinant protein was produced with TrueORF clone, RC222991. Click on the TrueORF clone link to view cDNA and protein sequences. Tag: C-terminal MYC/DDK Predicted MW: 83.5 kDa Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining Mass Spec Validation: This protein has been positively validated by MS/MS by Dr. Robert Moritz at The Institute of Systems Biology. Concentration: >50 ug/mL as determined by microplate BCA method Buffer and Storage: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions. Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. Protein Families: Transmembrane Protein Pathways: Glycine, serine and threonine metabolismTyrosine metabolismPhenylalanine metabolismbeta-Alanine metabolismMetabolic pathways

Protein Data

RefSeq: NP_033720	RefSeq Size: 2681	RefSeq ORF: 2271
LocusID: 314	Cytogenetic: 17q21
Synonyms : DAO2; RAO
Summary: Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes and ammonia in the presence of copper and quinone cofactor. This gene shows high sequence similarity to copper amine oxidases from various species ranging from bacteria to mammals. The protein contains several conserved motifs including the active site of amine oxidases and the histidine residues that likely bind copper. It may be a critical modulator of signal transmission in retina, possibly by degrading the biogenic amines dopamine, histamine, and putrescine. This gene may be a candidate gene for hereditary ocular diseases. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008].

Researchers who bought this clone have also purchased:

Related ORF Clones • Myc-DDK-tagged ORF clone of Homo sapiens amine oxidase, copper containing 2 (retina-specific) (AOC2), transcript variant 2 as transfection-ready DNA • Lenti ORF clone of Human amine oxidase, copper containing 2 (retina-specific) (AOC2), transcript variant 2 , Myc-DDK-tagged • Lenti ORF clone of Human amine oxidase, copper containing 2 (retina-specific) (AOC2), transcript variant 2, mGFP tagged • GFP-tagged ORF clone of Homo sapiens amine oxidase, copper containing 2 (retina-specific) (AOC2), transcript variant 2 as transfection-ready DNA • Myc-DDK-tagged ORF clone of Homo sapiens amine oxidase, copper containing 2 (retina-specific) (AOC2), transcript variant 2 as 200 ug transfection-ready DNA Related Lysate from OriGene • Transient overexpression lysate of amine oxidase, copper containing 2 (retina-specific) (AOC2), transcript variant 2 Anti-Tag Antibodies & WB Reagent • Anti-Tag Antibodies • Western Blot Reagent shRNA • AOC2 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector • AOC2 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector • Aoc2 - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector • AOC2 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector • Aoc2 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector Related Primer Pair qSTAR qPCR primer pairs against Homo sapiens gene AOC2

If you would like OriGene Technologies to prepare a purified protein in the quantity of your own interest, simply fill out the form and click Submit. OriGene will contact you.

Protein	Full Length Protein A domain of the protein Description of domain...
Tag	C-fusion N-fusion     Tag Description:
DNA or protein sequence of the final product
Preferred Expression Host	HEK293 E. coli Insect Cells Yeast
The main application with the purified protein	R&D reagent Cell-based Assay Animal Study Other, please specify:
* Quantity (µg)
Comments
* First Name
* Last Name
* Email Address
* Institution Name
* Country
* Phone