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Home Recombinant Human Proteins All MAP2K1 Proteins

MAP2K1 (NM_002755) Purified Human Protein

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Cat. No. Description Datasheet Price Availability*  
TP318460 Purified recombinant protein of Homo sapiens mitogen-activated protein kinase kinase 1 (MAP2K1), 20 ug (Larger pack size?) $680 In Stock
TA506070 Purified MAP2K1 (MEK1) mouse monoclonal antibody, Clone 5A11 $379 In Stock
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OriGene Data
Species:Human Expression Host:Human 293HEK cells
Expression cDNA Clone and Sequence Recombinant protein was produced with TrueORF clone, RC218460. Click on the TrueORF clone link to view cDNA and protein sequences.
Tag:C-terminal MYC/DDK Predicted MW:43.3 kDa
Purity:> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration:>50 ug/mL as determined by microplate BCA method
Buffer and Storage:25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Protein Families: Protein KinaseDruggable Genome
Protein Pathways: MAPK signaling pathwayErbB signaling pathwayChemokine signaling pathwayOocyte meiosisVascular smooth muscle contractionDorso-ventral axis formationMore Pathways >>
Protein Data
Protein Image
 

Reference Data
RefSeq: NP_002746 RefSeq Size: 2222 RefSeq ORF: 1182
LocusID: 5604 Cytogenetic: 15q22.1  
Synonyms : MAPKK1; MEK1; MKK1; PRKMK1
Summary: The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development. [provided by RefSeq, Jul
*: Inventory for certain proteins may be limited due to low expression level. Delivery time may vary from web posted schedule. Contact techsupport@origene.com for specific inventory information
**: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich

 

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