UGT2A1 (NM_006798) Purified Human Protein

Species: Human Expression Host: Human 293HEK cells Expression cDNA Clone and Sequence Recombinant protein was produced with TrueORF clone, RC217262. Click on the TrueORF clone link to view cDNA and protein sequences. Tag: C-terminal MYC/DDK Predicted MW: 59.7 kDa Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining Mass Spec Validation: This protein has been positively validated by MS/MS by Dr. Robert Moritz at The Institute of Systems Biology. Concentration: >50 ug/mL as determined by microplate BCA method Buffer and Storage: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions. Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. Protein Families: Transmembrane Protein Pathways: Pentose and glucuronate interconversionsAscorbate and aldarate metabolismAndrogen and estrogen metabolismStarch and sucrose metabolismRetinol metabolismPorphyrin and chlorophyll metabolismMore Pathways >>

Protein Data

RefSeq: NP_006789	RefSeq Size: 1766	RefSeq ORF: 1584
LocusID: 10941	Cytogenetic: 4q13
Synonyms :
Summary: The protein encoded by this gene belongs to the UDP-glycosyltransferase family, members of which catalyze biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase water solubility and enhance excretion. They are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This enzyme is expressed in the olfactory neuroepithelium, which lines the posterior nasal cavity and is exposed to a wide range of odorants and airborne toxic compounds. Hence, this protein has been suggested to be involved in clearing lipophilic odorant molecules from the sensory epithelium. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov

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Related ORF Clones • Myc-DDK-tagged ORF clone of Homo sapiens UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus (UGT2A1) as transfection-ready DNA • Lenti ORF clone of Human UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus (UGT2A1) , Myc-DDK-tagged • Lenti ORF clone of Human UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus (UGT2A1), mGFP tagged • GFP-tagged ORF clone of Homo sapiens UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus (UGT2A1) as transfection-ready DNA • Myc-DDK-tagged ORF clone of Homo sapiens UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus (UGT2A1) as 200 ug transfection-ready DNA Related Lysate from OriGene • Transient overexpression lysate of UDP glucuronosyltransferase 2 family, polypeptide A1 (UGT2A1) Anti-Tag Antibodies & WB Reagent • Anti-Tag Antibodies • Western Blot Reagent shRNA • UGT2A1 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector • UGT2A1 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector • Ugt2a1 - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector • UGT2A1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector • Ugt2a1 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector Related Primer Pair qSTAR qPCR primer pairs against Homo sapiens gene UGT2A1

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Protein	Full Length Protein A domain of the protein Description of domain...
Tag	C-fusion N-fusion     Tag Description:
DNA or protein sequence of the final product
Preferred Expression Host	HEK293 E. coli Insect Cells Yeast
The main application with the purified protein	R&D reagent Cell-based Assay Animal Study Other, please specify:
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