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Home Recombinant Human Proteins All TBXAS1 Proteins

TBXAS1 (NM_001061) Purified Human Protein

Specifications Citations Customer Service Product Documents
Cat. No. Description Datasheet Price Availability*  
TP308028 Recombinant protein of human thromboxane A synthase 1 (platelet) (TBXAS1), transcript variant TXS-I, 20 µg (Larger pack size?) 680 In Stock
TA501358 anti-TBXAS1 (Thromboxane synthase) mouse monoclonal antibody, clone 2C1 $379 In Stock
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OriGene Data
Species:Human Expression Host:HEK293 cells
Expression cDNA Clone or AA Sequence
Recombinant protein was produced with TrueORF clone, RC208028. Click on the TrueORF clone link to view cDNA and protein sequences.
Tag:C-terminal MYC/DDK Predicted MW:60.5 kDa
Purity:> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration:>50 ug/mL as determined by microplate BCA method
Buffer:25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Protein Families: P450Druggable Genome
Protein Pathways: Arachidonic acid metabolismMetabolic pathways
Protein Data
Protein Image
 

Reference Data
RefSeq: NP_001052 RefSeq Size: 1946 RefSeq ORF: 1605
LocusID: 6916 Cytogenetic: 7q34-q35  
Synonyms : BDPLT14; CYP5; CYP5A1; GHOSAL; THAS; TS; TXAS; TXS
Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to thromboxane A2, a potent vasoconstrictor and inducer of platelet aggregation. The enzyme plays a role in several pathophysiological processes including hemostasis, cardiovascular disease, and stroke. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008].
*: Inventory for certain proteins may be limited due to low expression level. Delivery time may vary from web posted schedule. Contact techsupport@origene.com for specific inventory information
**: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich

 

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