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Home Recombinant Human Proteins All CLDN1 Proteins

CLDN1 (NM_021101) Purified Human Protein

Specifications Citations Customer Service Product Documents
Cat. No. Description Datasheet Price Availability*  
TP304466 Recombinant protein of human claudin 1 (CLDN1), 20 ug (Larger pack size?) 680 In Stock
TA312396 Rabbit polyclonal Claudin 1 (Ab-210) antibody $325 In Stock
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Also for CLDN1 (NM_021101)
cDNA Clone shRNA/siRNA Primer Pair Protein Antibody

OriGene Data
Species:Human Expression Host:HEK293 cells
Expression cDNA Clone or AA Sequence
Recombinant protein was produced with TrueORF clone, RC204466. Click on the TrueORF clone link to view cDNA and protein sequences.
Tag:C-terminal MYC/DDK Predicted MW:22.6 kDa
Purity:> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration:>50 ug/mL as determined by microplate BCA method
Buffer:25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Protein Families: Transmembrane
Protein Pathways: Cell adhesion molecules (CAMs)Tight junctionLeukocyte transendothelial migrationPathogenic Escherichia coli infection
Protein Data
Protein Image
 

Reference Data
RefSeq: NP_066924 RefSeq Size: 3445 RefSeq ORF: 636
LocusID: 9076 Cytogenetic: 3q28  
Synonyms : CLD1; ILVASC; SEMP1
Summary: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome. [provided by RefSeq, Jul 2008].
*: Inventory for certain proteins may be limited due to low expression level. Delivery time may vary from web posted schedule. Contact techsupport@origene.com for specific inventory information
**: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich

 

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