Promotion ends on May 1st.
Also for CLDN1 (NM_021101)
|Expression cDNA Clone or AA Sequence
Recombinant protein was produced with TrueORF clone, RC204466
. Click on the TrueORF clone link to view cDNA and protein sequences.
||Predicted MW:||22.6 kDa|
|Purity:||> 80% as determined by SDS-PAGE and Coomassie blue staining|
|Concentration:||>50 ug/mL as determined by microplate BCA method|
|Buffer:||25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.|
||Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
||Cell adhesion molecules (CAMs)Tight junctionLeukocyte transendothelial migrationPathogenic Escherichia coli infection
||RefSeq Size: 3445
||RefSeq ORF: 636|
|Synonyms : CLD1; ILVASC; SEMP1|
|Summary: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome. [provided by RefSeq, Jul 2008]. |
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**: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich