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Home Recombinant Human Proteins All GMPS Proteins

GMPS (NM_003875) Purified Human Protein

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Cat. No. Description Datasheet Price Availability*  
TP304267 Recombinant protein of human guanine monphosphate synthetase (GMPS), 20 ug (Larger pack size?) $680
$398
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TA50011-100 4C5, Anti-DDK monoclonal antibody (100 μL) $248 In Stock
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OriGene Data
Species:Human Expression Host:HEK293
Expression cDNA Clone or AA Sequence
Recombinant protein was produced with TrueORF clone, RC204267. Click on the TrueORF clone link to view cDNA and protein sequences.
Tag:C-terminal MYC/DDK Predicted MW:76.5 kDa
Purity:> 80% as determined by SDS-PAGE and Coomassie blue staining
Mass Spec Validation: This protein has been positively validated by MS/MS by Dr. Robert Moritz at The Institute of Systems Biology.
Concentration:>50 ug/mL as determined by microplate BCA method
Buffer:25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Protein Families: Stem cell - Pluripotency
Protein Pathways: Purine metabolismDrug metabolism - other enzymesMetabolic pathways
Protein Data
Protein Image
 

Reference Data
RefSeq: NP_003866 RefSeq Size: 2457 RefSeq ORF: 2082
LocusID: 8833 Cytogenetic: 3q24  
Synonyms : MLL/GMPS fusion protein; GMP synthase; GMP synthetase; glutamine amidotransferase; guanine monophosphate synthetase; guanosine 5'-monophosphate synthase; guanine monphosphate synthetase
Summary: In the de novo synthesis of purine nucleotides, IMP is the branch point metabolite at which point the pathway diverges to the synthesis of either guanine or adenine nucleotides. In the guanine nucleotide pathway, there are 2 enzymes involved in converting IMP to GMP, namely IMP dehydrogenase (IMPD1), which catalyzes the oxidation of IMP to XMP, and GMP synthetase, which catalyzes the amination of XMP to GMP. [provided by RefSeq, Jul 2008].
*: Inventory for certain proteins may be limited due to low expression level. Delivery time may vary from web posted schedule. Contact techsupport@origene.com for specific inventory information
**: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich

 

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