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Home Recombinant Human Proteins All PLA2G12A Proteins

PLA2G12A (NM_030821) Purified Human Protein

Specifications Citations Customer Service Product Documents
Cat. No. Description Datasheet Price Availability*  
TP302955 Recombinant protein of human phospholipase A2, group XIIA (PLA2G12A), 20 µg (Larger pack size?) 680 In Stock
TA308641 Rabbit polyclonal antibody to Phospholipase A2 XIIA (phospholipase A2, group XIIA) $325 3-7 Days
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Also for PLA2G12A (NM_030821)
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OriGene Data
Species:Human Expression Host:HEK293 cells
Expression cDNA Clone or AA Sequence
Recombinant protein was produced with TrueORF clone, RC202955. Click on the TrueORF clone link to view cDNA and protein sequences.
Tag:C-terminal MYC/DDK Predicted MW:20.9 kDa
Purity:> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration:>50 ug/mL as determined by microplate BCA method
Buffer:25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Protein Families: Secreted ProteinDruggable Genome
Protein Pathways: Glycerophospholipid metabolismEther lipid metabolismArachidonic acid metabolismLinoleic acid metabolismalpha-Linolenic acid metabolismMetabolic pathwaysMore Pathways >>
Protein Data
Protein Image
 

Reference Data
RefSeq: NP_110448 RefSeq Size: 1699 RefSeq ORF: 570
LocusID: 81579 Cytogenetic: 4q25  
Synonyms : GXII; PLA2G12; ROSSY
Summary: Secreted phospholipase A2 (sPLA2) enzymes liberate arachidonic acid from phospholipids for production of eicosanoids and exert a variety of physiologic and pathologic effects. Group XII sPLA2s, such as PLA2G12A, have relatively low specific activity and are structurally and functionally distinct from other sPLA2s (Gelb et al., 2000 [PubMed 11031251]).[supplied by OMIM, Mar 2008]. Sequence Note: The RefSeq transcript and protein were derived from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The extent of this RefSeq transcript is supported by transcript alignments. ##Evidence-Data-START## Transcript exon combination :: BI667755.1, BC017218.2 [ECO:0000332] RNAseq introns :: single sample supports all introns ERS025084, ERS025087 [ECO:0000348] ##Evidence-Data-END##
*: Inventory for certain proteins may be limited due to low expression level. Delivery time may vary from web posted schedule. Contact techsupport@origene.com for specific inventory information
**: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich

 

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