IL17RA (NM_014339) Purified Human Protein

Species: Human Expression Host: Human 293HEK cells Expression cDNA Clone and Sequence Recombinant protein was produced with TrueORF clone, RC202390. Click on the TrueORF clone link to view cDNA and protein sequences. Tag: C-terminal MYC/DDK Predicted MW: 93.2 kDa Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining Mass Spec Validation: This protein has been positively validated by MS/MS by Dr. Robert Moritz at The Institute of Systems Biology. Concentration: >50 ug/mL as determined by microplate BCA method Buffer and Storage: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions. Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. Protein Families: TransmembraneDruggable Genome Protein Pathways: Cytokine-cytokine receptor interaction

Protein Data

RefSeq: NP_055154	RefSeq Size: 3429	RefSeq ORF: 2601
LocusID: 23765	Cytogenetic: 22q11.1
Synonyms : CANDF5; CD217; CDw217; hIL-17R; IL-17RA; IL17R
Summary: Interleukin 17A (IL17A)is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. [provided by RefSeq, Jul 2008].

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Related ORF Clones • Myc-DDK-tagged ORF clone of Homo sapiens interleukin 17 receptor A (IL17RA) as transfection-ready DNA • GFP-tagged ORF clone of Homo sapiens interleukin 17 receptor A (IL17RA) as transfection-ready DNA Validated Antibodies • Rabbit Monoclonal antibody against IL-17R alpha (IL17RA) • Rabbit polyclonal anti-IL17RA antibody • Rabbit polyclonal anti-IL17RA antibody Anti-Tag Antibodies & WB Reagent • Anti-Tag Antibodies • Western Blot Reagent shRNA • IL17RA - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector • IL17RA - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector • Il17ra - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector • IL17RA - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector • Il17ra - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector Related Primer Pair qSTAR qPCR primer pairs against Homo sapiens gene IL17RA

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Protein	Full Length Protein A domain of the protein Description of domain...
Tag	C-fusion N-fusion     Tag Description:
DNA or protein sequence of the final product
Preferred Expression Host	HEK293 E. coli Insect Cells Yeast
The main application with the purified protein	R&D reagent Cell-based Assay Animal Study Other, please specify:
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