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Home Recombinant Human Proteins All STIP1 Proteins

STIP1 (NM_006819) Purified Human Protein

Specifications Citations Customer Service Product Documents
Cat. No. Description Datasheet Price Availability*  
TP301084 Recombinant protein of human stress-induced-phosphoprotein 1 (STIP1), 20 ug (Larger pack size?) $680 In Stock
TA308465 Rabbit Polyclonal antibody to STIP1 (stress-induced-phosphoprotein 1) $325 In Stock
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Also for STIP1 (NM_006819)
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OriGene Data
Species:Human Expression Host:HEK293
Expression cDNA Clone or AA Sequence
Recombinant protein was produced with TrueORF clone, RC201084. Click on the TrueORF clone link to view cDNA and protein sequences.
Tag:C-terminal MYC/DDK Predicted MW:62.5 kDa
Purity:> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration:>50 ug/mL as determined by microplate BCA method
Buffer:25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Protein Families: Stem cell - Pluripotency
Protein Pathways: Prion diseases
Protein Data
Protein Image
 

Reference Data
RefSeq: NP_006810 RefSeq Size: 2219 RefSeq ORF: 1632
LocusID: 10963 Cytogenetic: 11q13  
Synonyms : HEL-S-94n; HOP; IEF-SSP-3521; P60; STI1; STI1L
Summary: STIP1 is an adaptor protein that coordinates the functions of HSP70 (see HSPA1A; MIM 140550) and HSP90 (see HSP90AA1; MIM 140571) in protein folding. It is thought to assist in the transfer of proteins from HSP70 to HSP90 by binding both HSP90 and substrate-bound HSP70. STIP1 also stimulates the ATPase activity of HSP70 and inhibits the ATPase activity of HSP90, suggesting that it regulates both the conformations and ATPase cycles of these chaperones (Song and Masison, 2005 [PubMed 16100115]).[supplied by OMIM, Jul 2009].
*: Inventory for certain proteins may be limited due to low expression level. Delivery time may vary from web posted schedule. Contact techsupport@origene.com for specific inventory information
**: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich

 

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