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Home Recombinant Human Proteins All UPP1 Proteins

UPP1 (NM_003364) Purified Human Protein

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Cat. No. Description Datasheet Price Availability*  
TP300406 Recombinant protein of human uridine phosphorylase 1 (UPP1), transcript variant 1, 20 ug (Larger pack size?) 680
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OriGene Data
Species:Human Expression Host:HEK293 cells
Expression cDNA Clone or AA Sequence
Recombinant protein was produced with TrueORF clone, RC200406. Click on the TrueORF clone link to view cDNA and protein sequences.
Tag:C-terminal MYC/DDK Predicted MW:33.8 kDa
Purity:> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration:>50 ug/mL as determined by microplate BCA method
Buffer:25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Protein Families:
Protein Pathways: Pyrimidine metabolismDrug metabolism - other enzymesMetabolic pathways
Protein Data
Protein Image

Reference Data
RefSeq: NP_003355 RefSeq Size: 1796 RefSeq ORF: 933
LocusID: 7378 Cytogenetic: 7p12.3  
Summary: The 2 known types of pyrimidine nucleoside phosphorylases, uridine phosphorylase (UP; EC and thymidine phosphorylase (TP; EC, in the presence of orthophosphate, catalyze the reversible phosphorolysis of uridine and thymidine or deoxyuridine, respectively, to free bases and ribose-1-phosphate or deoxyribose-1-phosphate. Pyrimidine nucleoside phosphorylases can add ribose or deoxyribose to pyrimidine bases to form nucleosides that can be incorporated into RNA or DNA (Watanabe and Uchida, 1995 [PubMed 7488099]).[supplied by OMIM, Aug 2009]. Transcript Variant: This variant (7) differs in the 5' region, and lacks two exons and uses an alternate splice site in the central region, compared to variant 3. This variant is represented as non-coding because the use of the 5'-most expected translational start codon, as used in variant 3, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD). ##Evidence-Data-START## Transcript exon combination :: BC053592.1 [ECO:0000332] RNAseq introns :: single sample supports all introns ERS025083, ERS025086 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.
*: Inventory for certain proteins may be limited due to low expression level. Delivery time may vary from web posted schedule. Contact techsupport@origene.com for specific inventory information
**: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich


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