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Home TrueClone Abcc5 Clone

Abcc5 (NM_013790) Mouse cDNA Clone

Specifications Citations Clones of Other Species Product Documents
SKU Description Price Availibility*  
MC224446 Abcc5 (untagged) - Mouse ATP-binding cassette, sub-family C (CFTR/MRP), member 5 (Abcc5), transcript variant 1, (10ug) NM_013790.2, 10ug $1720 7 weeks
TF81001 TurboFectin, High performance Transfection reagent (1ml/vial) $420 In Stock
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OriGene Data
Vector:pCMV6 Entry Insert Size: 4311 Restriction Site: SgfI-MluI
Sequence Data: Fully Sequenced ORF         
OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reference Data
RefSeq: NM_013790.2, NP_038818
RefSeq Size: 4311 RefSeq ORF: 4310
Synonyms : 2900011L11Rik; Abcc5a; Abcc5b; AI132311; Mrp5
LocusID: 27416 Cytogenetic: 16
Summary: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The human protein functions in the cellular export of its substrate, cyclic nucleotides. This export contributes to the degradation of phosphodiesterases and possibly an elimination pathway for cyclic nucleotides. Studies show that the human protein provides resistance to thiopurine anticancer drugs, 6-mercatopurine and thioguanine, and the anti-HIV drug 9-(2-phosphonylmethoxyethyl)adenine. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

Transcript Variant: This variant (1) is the longer transcript and encodes the longer isoform (1). COMPLETENESS: complete on the 3' end.

* Delivery time is an estimate in business days. Occasional delays may occur due to unforeseen complexities in the preparation of your construct. International customers may expect an additional 1-2 weeks in shipping

 

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